CAJ | 학술논문

目的探讨支气管激发试验(bronchial provocation test,BPT)在慢性咳嗽及咳嗽变异型哮喘(cough variant asthma,CVA)诊断中的应用价值.方法对1 155例慢性咳嗽患者进行乙酰甲胆碱BPT,检测其气道高反应性.结果 1 155例慢性咳嗽患者中,各年龄组肺功能参数比较差异无统计学意义.BPT阳性584例,阴性571例,阳件率50.6%.确诊为CVA 547例;其余37例BPt阳性慢性咳嗽患者中25例为感染后咳嗽,12例为慢性支气管炎.BPT诊断CVA的特异度为93.6%.小于30岁年龄组CVA比例最高,占慢性咳嗽68.8%;≥60岁组CVA百分比最低,为23.5%.结论 CVA足慢性咳嗽的主要病因,对不明原因的慢性咳嗽患者应及时进行BPT,有助于早期明确诊断并施以正确治疗.
목적 탐토지기관격발시험(bronchial provocation test,BPT)재만성해수급해수변이형효천(cough variant asthma,CVA)진단중적응용개치.방법 대1 155례만성해수환자진행을선갑담감BPT,검측기기도고반응성.결과 1 155례만성해수환자중,각년령조폐공능삼수비교차이무통계학의의.BPT양성584례,음성571례,양건솔50.6%.학진위CVA 547례;기여37례BPt양성만성해수환자중25례위감염후해수,12례위만성지기관염.BPT진단CVA적특이도위93.6%.소우30세년령조CVA비례최고,점만성해수68.8%;≥60세조CVA백분비최저,위23.5%.결론 CVA족만성해수적주요병인,대불명원인적만성해수환자응급시진행BPT,유조우조기명학진단병시이정학치료.
Objective To investigate the etiological diagnosis utilization value of bronchial provocation test(BPT) in patients with chronic cough variant asthrna(CVA).Methods BPT was performed to assess the bronchial responsiveness by inhaling methacholine in 1 155 patients with chronic cough.Results There was no significant difference of pulmonary function in different age groups.The positive rate of BPT was 50.6 (584/1 155,285 males,299 females),in those patients with positive result,547 patients were diagnosed as CVA,25 patients as post-infection cough,and 12 patients as chronic bronchitis.BPT specificity was 93.9 %.The population under 30 years old had the highest CVA diagnostic rate of 68.8% and those over 60 years old had the lowest diagnostic rate of 23.5%.The two groups had significant difference when compared with other age groups respectively.Conclusions CVA is the main cause of chronic cough.BPT is a simple and effective method in the diagnosis of CVA at early stage.