中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2011年
2期
109-111
,共3页
崔兆清%章阳%姚玉民%孙善平%周长鑫
崔兆清%章暘%姚玉民%孫善平%週長鑫
최조청%장양%요옥민%손선평%주장흠
甲状腺疾病%尿碘
甲狀腺疾病%尿碘
갑상선질병%뇨전
Thyroid disease%Urinary iodine
目的 探讨聊城地区尿碘水平与甲状腺疾病的关系.方法 测定聊城地区甲状腺疾病组和正常对照组的血清TSH、FT3、FT4,甲状腺过氧化物酶抗体(TPOAb),甲状腺球蛋白抗体(TGAb)、甲状腺B超及尿碘.结果正常对照组的尿碘中位数为108μg/L,甲状腺功能异常及甲状腺结节患者的尿碘中位数为263μg/L,显著高于正常对照组,差异有统计学意义(P<0.01);在甲状腺功能异常和甲状腺结节患者中,尿碘浓度>300μg/L者超过50%,高于对照组的35%,差异有统计学意义(P<0.01);尿碘与甲状腺功能(FT3、FT4、TSH、TPO、TGA)及甲状腺结节之间无明确的相关性(P>0.05).结论 聊城地区属碘充足地区,碘过量会增加甲状腺疾病发生率,尿碘测定有助于指导个体化补碘.
目的 探討聊城地區尿碘水平與甲狀腺疾病的關繫.方法 測定聊城地區甲狀腺疾病組和正常對照組的血清TSH、FT3、FT4,甲狀腺過氧化物酶抗體(TPOAb),甲狀腺毬蛋白抗體(TGAb)、甲狀腺B超及尿碘.結果正常對照組的尿碘中位數為108μg/L,甲狀腺功能異常及甲狀腺結節患者的尿碘中位數為263μg/L,顯著高于正常對照組,差異有統計學意義(P<0.01);在甲狀腺功能異常和甲狀腺結節患者中,尿碘濃度>300μg/L者超過50%,高于對照組的35%,差異有統計學意義(P<0.01);尿碘與甲狀腺功能(FT3、FT4、TSH、TPO、TGA)及甲狀腺結節之間無明確的相關性(P>0.05).結論 聊城地區屬碘充足地區,碘過量會增加甲狀腺疾病髮生率,尿碘測定有助于指導箇體化補碘.
목적 탐토료성지구뇨전수평여갑상선질병적관계.방법 측정료성지구갑상선질병조화정상대조조적혈청TSH、FT3、FT4,갑상선과양화물매항체(TPOAb),갑상선구단백항체(TGAb)、갑상선B초급뇨전.결과정상대조조적뇨전중위수위108μg/L,갑상선공능이상급갑상선결절환자적뇨전중위수위263μg/L,현저고우정상대조조,차이유통계학의의(P<0.01);재갑상선공능이상화갑상선결절환자중,뇨전농도>300μg/L자초과50%,고우대조조적35%,차이유통계학의의(P<0.01);뇨전여갑상선공능(FT3、FT4、TSH、TPO、TGA)급갑상선결절지간무명학적상관성(P>0.05).결론 료성지구속전충족지구,전과량회증가갑상선질병발생솔,뇨전측정유조우지도개체화보전.
Objective To investigate relationship between urinary iodine level and thyroid diseases in Liaocheng city.Methods Level of serum TSH,FT3,FT4,TPOAb,TGAb and urinary iodine in thyroid disease group and normal control group was detected respectively.Results The median concentration of urinary iodine in normal control group in Liaocheng was 108μg/L.The median urinary iodine level in patients with thyroid dysfunction and thyroid nodal diseases was higher than that in normal control group(P<0.01).In patients with thyroid dysfunction and thyroid nodal diseases,the concentration of urinary iodine Was above 300μg/L and distribution frequency Was much higher than that in control group(P<0.01).There was no correlation between urinary iodine and thyroid function or thyroid nodule(P>0.05).Conclusions Iodine uptake in Liaocheng is sufficient.Additional uptake of iodine increases the incidence of thyroid diseases.Urine iodine detection helps to guide iodine supplementation in individual.
