临床耳鼻咽喉科杂志
臨床耳鼻嚥喉科雜誌
림상이비인후과잡지
LINCHUANG ER-BL-YANHOUKE ZAZHL
2000年
10期
460-461
,共2页
豚鼠毛细胞静纤毛连接椭圆囊斑
豚鼠毛細胞靜纖毛連接橢圓囊斑
돈서모세포정섬모련접타원낭반
Guinea pigs Hair cell Stereociliary cross-links Utricle
目的：探讨豚鼠椭圆囊斑毛细胞静纤毛束间的相互连接形式及其生理意义。方法：用扫描电镜和透射电镜观察豚鼠椭圆囊斑毛细胞静纤毛束间的相互连接。结果：豚鼠椭圆囊斑毛细胞静纤毛束间存在3种相互连接形式：①顶部连接：自短纤毛顶至长纤毛的上行连接；②侧连接：同行静纤毛间的云雾状连接；③行间连接：邻近行间的连接。结论：3种连接的存在可将纤毛束连为一体。推测当纤毛偏转时，所有静纤毛可能形成一个整体依次移动，牵拉或放松顶部连接，从而改变纤毛顶端膜机械门控离子通道的电导，使细胞膜离子通透性改变，细胞膜去极化或超极化，导致神经兴奋或抑制。
目的：探討豚鼠橢圓囊斑毛細胞靜纖毛束間的相互連接形式及其生理意義。方法：用掃描電鏡和透射電鏡觀察豚鼠橢圓囊斑毛細胞靜纖毛束間的相互連接。結果：豚鼠橢圓囊斑毛細胞靜纖毛束間存在3種相互連接形式：①頂部連接：自短纖毛頂至長纖毛的上行連接；②側連接：同行靜纖毛間的雲霧狀連接；③行間連接：鄰近行間的連接。結論：3種連接的存在可將纖毛束連為一體。推測噹纖毛偏轉時，所有靜纖毛可能形成一箇整體依次移動，牽拉或放鬆頂部連接，從而改變纖毛頂耑膜機械門控離子通道的電導，使細胞膜離子通透性改變，細胞膜去極化或超極化，導緻神經興奮或抑製。
목적：탐토돈서타원낭반모세포정섬모속간적상호련접형식급기생리의의。방법：용소묘전경화투사전경관찰돈서타원낭반모세포정섬모속간적상호련접。결과：돈서타원낭반모세포정섬모속간존재3충상호련접형식：①정부련접：자단섬모정지장섬모적상행련접；②측련접：동행정섬모간적운무상련접；③행간련접：린근행간적련접。결론：3충련접적존재가장섬모속련위일체。추측당섬모편전시，소유정섬모가능형성일개정체의차이동，견랍혹방송정부련접，종이개변섬모정단막궤계문공리자통도적전도，사세포막리자통투성개변，세포막거겁화혹초겁화，도치신경흥강혹억제。
Objective:To observe the cross-links between stereocilia on guinea pig utricle hair cells. Method:Twenty-four utricles from pigmented guinea pigs were examined using high resolution scanning (SEM)andtransmission electron microscopy(TEM). Result:an extensive network of cross-links occurs between stereociliaof utricle hair cells. These links fall into three categories. Upward-pointing links:from the tips of shorterstereocilia to the side of the adjacent taller stereocilia;Side-to-side links:between stereocilia of the same row;Row-to-row links :between adjacent rows. Conclusion :The existence of the stereociliary cross-links binds the hairbundles together and may be associated with the transduction process.
