CAJ | 학술논문

目的考察凹凸棒石对中药丹参及复方丹参滴丸水煎提取液中有效成分丹参酮Ⅰ、丹参酮Ⅱ_A的吸附作用.方法以煎出总固体物量和丹参酮Ⅰ、丹参酮Ⅱ_A含量为指标,采用高效液相色谱法测定丹参酮Ⅰ、丹参酮Ⅱ_A的含量,分别考察普通凹凸棒石与酸化凹凸棒石对中药丹参和复方丹参滴丸水煎提取液的吸附澄清作用.结果普通凹凸棒石对中药丹参及复方丹参滴丸水煎提取液中总固体物量无明显改善,对丹参酮Ⅰ、丹参酮Ⅱ_A的含量略有影响;酸化凹凸棒石使中药丹参及复方丹参滴丸水煎液中浸出总固体物含量明显减少,对丹参酮Ⅰ、丹参酮Ⅱ_A的含量影响较小.结论酸化凹凸棒石可作为丹参药材和复方丹参滴丸水煎提取液的吸附澄清剂.
목적 고찰요철봉석대중약단삼급복방단삼적환수전제취액중유효성분단삼동Ⅰ、단삼동Ⅱ_A적흡부작용.방법 이전출총고체물량화단삼동Ⅰ、단삼동Ⅱ_A함량위지표,채용고효액상색보법측정단삼동Ⅰ、단삼동Ⅱ_A적함량,분별고찰보통요철봉석여산화요철봉석대중약단삼화복방단삼적환수전제취액적흡부징청작용.결과 보통요철봉석대중약단삼급복방단삼적환수전제취액중총고체물량무명현개선,대단삼동Ⅰ、단삼동Ⅱ_A적함량략유영향;산화요철봉석사중약단삼급복방단삼적환수전액중침출총고체물함량명현감소,대단삼동Ⅰ、단삼동Ⅱ_A적함량영향교소.결론 산화요철봉석가작위단삼약재화복방단삼적환수전제취액적흡부징청제.
Purpose To investigate the adsorptive effect of attapulgite on Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Mihiorrhizae and Composite Dansen Pill.Methods Using the amount of solid component and the content of Tanshinone Ⅰ and Tanshinone Ⅱ_A as index,the adsorptive effect of common attapulgite and acidified attapulgite on decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill was investigated respectively and the content of Tanshinone Ⅰ and Tanshinone Ⅱ_A was determined by HPLC.Results Common attapulgite could not markedly decreased the amount of solid component and had a litfle effect on the content of Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.The acidified attapulgite could obviously decrease the amount of solid component and had a little effect on the content of Tanshinone Ⅰ and TanshinoneⅡ_A in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.Conclusion Acidified attapulgite could be used as adsorptive clarifier in decoction of Radix et Rhizoma Salviae Miltiorrhizae and Composite Dansen Pill.