国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
12期
1754-1756
,共3页
米索前列醇%剖宫产%疤痕子宫%子宫收缩
米索前列醇%剖宮產%疤痕子宮%子宮收縮
미색전렬순%부궁산%파흔자궁%자궁수축
Misoprostol%Cesarean section%Scar uterus%Uterine contraction
目的 观察米索前列醇应用与疤痕子宫剖宫产术中对子宫收缩的促进作用.方法 选取2010年5月至2011年10月期间在我院需行刮宫产的有疤痕子宫的84例产妇,随机分为观察组及对照组各42例,对照组在胎儿娩出后静脉滴注缩宫素20U,子宫体肌注20U,观察组在对照组用药基础上加用米索前列醇400(磺),直肠用药,观察两组术中及术后出血量、用药不良反应.结果 观察组术中及术后出血量分别为(228.73±30.94)ml、(110.32±45.71)ml,对照组分别为(294.88±50.42)ml、(160.29±60.84)ml,观察组术中及术后2h出血量均明显少于对照组,比较差异有显著性(P＜0.05);观察组药物不良反应发生率9.52％,对照组0,比较差异无显著性(P＞0.05).结论 米索前列醇直肠放药,对于疤痕子宫剖宫产的产妇促进子宫收缩作用较单一使用缩宫素效果好,并且用药安全、简单,值得临床推广.
目的 觀察米索前列醇應用與疤痕子宮剖宮產術中對子宮收縮的促進作用.方法 選取2010年5月至2011年10月期間在我院需行颳宮產的有疤痕子宮的84例產婦,隨機分為觀察組及對照組各42例,對照組在胎兒娩齣後靜脈滴註縮宮素20U,子宮體肌註20U,觀察組在對照組用藥基礎上加用米索前列醇400(磺),直腸用藥,觀察兩組術中及術後齣血量、用藥不良反應.結果 觀察組術中及術後齣血量分彆為(228.73±30.94)ml、(110.32±45.71)ml,對照組分彆為(294.88±50.42)ml、(160.29±60.84)ml,觀察組術中及術後2h齣血量均明顯少于對照組,比較差異有顯著性(P＜0.05);觀察組藥物不良反應髮生率9.52％,對照組0,比較差異無顯著性(P＞0.05).結論 米索前列醇直腸放藥,對于疤痕子宮剖宮產的產婦促進子宮收縮作用較單一使用縮宮素效果好,併且用藥安全、簡單,值得臨床推廣.
목적 관찰미색전렬순응용여파흔자궁부궁산술중대자궁수축적촉진작용.방법 선취2010년5월지2011년10월기간재아원수행괄궁산적유파흔자궁적84례산부,수궤분위관찰조급대조조각42례,대조조재태인면출후정맥적주축궁소20U,자궁체기주20U,관찰조재대조조용약기출상가용미색전렬순400(광),직장용약,관찰량조술중급술후출혈량、용약불량반응.결과 관찰조술중급술후출혈량분별위(228.73±30.94)ml、(110.32±45.71)ml,대조조분별위(294.88±50.42)ml、(160.29±60.84)ml,관찰조술중급술후2h출혈량균명현소우대조조,비교차이유현저성(P＜0.05);관찰조약물불량반응발생솔9.52％,대조조0,비교차이무현저성(P＞0.05).결론 미색전렬순직장방약,대우파흔자궁부궁산적산부촉진자궁수축작용교단일사용축궁소효과호,병차용약안전、간단,치득림상추엄.
Objective To observe the effect of misoprostol to promote uterine contraction in scar uterus cesarean section.Methods 84 cases of puerpera with scar uterus needing cesarean section in our hospital from May 2010 to October 2011 were selected.All patients were randomly divided into two groups.The control group had 42 cases which applied intravenous drip 20U of oxytocin after the expulsion of fetus,and uterine body intramuscular injection 20U.The observation group had 42 cases which applied misoprostol 400 μg used in rectum on the basis of control group.The blood loss during and after the operation and adverse drug reaction were observed.Results The blood loss of the observation group during and after the operation were ( 228.73±30.94 ) ml,( 110.32 ± 45.71 )nl,and ( 294.88 ± 50.42 )ml,( 160.29 ± 60.84 ) ml in the control group.The blood loss of the observation group during and 2 hours after the operation were obviously less than those of control group.It was significantly different (P＜0.05).Adverse drug reaction incidence rate of the observation group was 9.52％,and 0 in the control group.There was no statistical significant difference (P＞0.05).Conclusion Misoprostol using in rectum has better effects than the single use of oxytocin to promote uterine contraction for puerpera of scar uterus cesarean section.And it' s safe,simple,deserving clinical application.
