中国医药
中國醫藥
중국의약
CHINA MEDICINE
2010年
11期
1063-1064
,共2页
婴儿,新生%呼吸系统%感染
嬰兒,新生%呼吸繫統%感染
영인,신생%호흡계통%감염
Infant,newborn%Respiratory system%Infection
目的 了解新生儿呼吸道感染病原体的分布及耐药情况,为临床预防和治疗新生儿感染提供防治依据. 方法 采用法国生物梅里埃ATB系统软件,统计分析68例患儿呼吸道标本分离菌种类及药敏结果;用酶联免疫吸附法对其中60例患儿进行肺炎支原体、肺炎衣原体、呼吸道合胞病毒、腺病毒血清抗体检测. 结果 肺炎克雷伯菌肺炎亚种(16株,23.5%)、大肠埃希菌(12株,17.6%)、金黄色匍萄球菌(12株,17.6%)为主要病原菌;革兰阴性杆菌对亚胺培南、美洛培南、头孢吡肟、哌拉西林+他唑巴坦等较敏感,葡萄球菌对青霉素耐药最明显.60例患儿检出呼吸道合胞病毒26株(43.3%);肺炎支原体17株(28.3%);肺炎衣原体8株(13.3%);腺病毒4株(6.7%),其他5株(8.3%). 结论 新生儿呼吸道感染的原因很复杂,临床首先应根据实际情况采取措施,清除新生儿的感染诱因,然后根据检测结果合理使用抗生素,避免疾病反复和耐药菌产生.
目的 瞭解新生兒呼吸道感染病原體的分佈及耐藥情況,為臨床預防和治療新生兒感染提供防治依據. 方法 採用法國生物梅裏埃ATB繫統軟件,統計分析68例患兒呼吸道標本分離菌種類及藥敏結果;用酶聯免疫吸附法對其中60例患兒進行肺炎支原體、肺炎衣原體、呼吸道閤胞病毒、腺病毒血清抗體檢測. 結果 肺炎剋雷伯菌肺炎亞種(16株,23.5%)、大腸埃希菌(12株,17.6%)、金黃色匍萄毬菌(12株,17.6%)為主要病原菌;革蘭陰性桿菌對亞胺培南、美洛培南、頭孢吡肟、哌拉西林+他唑巴坦等較敏感,葡萄毬菌對青黴素耐藥最明顯.60例患兒檢齣呼吸道閤胞病毒26株(43.3%);肺炎支原體17株(28.3%);肺炎衣原體8株(13.3%);腺病毒4株(6.7%),其他5株(8.3%). 結論 新生兒呼吸道感染的原因很複雜,臨床首先應根據實際情況採取措施,清除新生兒的感染誘因,然後根據檢測結果閤理使用抗生素,避免疾病反複和耐藥菌產生.
목적 료해신생인호흡도감염병원체적분포급내약정황,위림상예방화치료신생인감염제공방치의거. 방법 채용법국생물매리애ATB계통연건,통계분석68례환인호흡도표본분리균충류급약민결과;용매련면역흡부법대기중60례환인진행폐염지원체、폐염의원체、호흡도합포병독、선병독혈청항체검측. 결과 폐염극뢰백균폐염아충(16주,23.5%)、대장애희균(12주,17.6%)、금황색포도구균(12주,17.6%)위주요병원균;혁란음성간균대아알배남、미락배남、두포필우、고랍서림+타서파탄등교민감,포도구균대청매소내약최명현.60례환인검출호흡도합포병독26주(43.3%);폐염지원체17주(28.3%);폐염의원체8주(13.3%);선병독4주(6.7%),기타5주(8.3%). 결론 신생인호흡도감염적원인흔복잡,림상수선응근거실제정황채취조시,청제신생인적감염유인,연후근거검측결과합리사용항생소,피면질병반복화내약균산생.
Objective To evaluate the distribution and drug resistance of pathogen causing neonatal lower respiratory infection,and to provide evidence for clinic to prevention and cure neonatal infection. Methods The type of separated bacteria and the drug resistance from the respiratory specimens of 68 neonatals with respiratory tract infection in the hospital were analyzed.Respiratory Syncytial virus\Mycoplasma pneumoniae\tests were performed by enzyme-linked immunoabsorbent assay. Results Escherichia coli was isolated 12(17.6%)and klebsiella pneumoniae subspecies was 16(23.5%)strains,12(10.3%)were staphylococcus aureus from 68 strains.Gram negative was susceptible to imipenem,ciprofloxacin,ceftazidime and amikacin.Staphylococcus aureus was resistant to penicillin Severity,while respiratory Syncytial virus,mycoplasma pneumoniae,Cp,ADV were prevalent in neonatal respiratory tract infection Conclusion Lower respiratory tract infection in neonatal is complicated and it is important to prevent the occurrence of drug resistance.
