中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2008年
1期
5-7
,共3页
张俊%徐迎胜%郑菊阳%张朔%康德瑄%樊东升
張俊%徐迎勝%鄭菊暘%張朔%康德瑄%樊東升
장준%서영성%정국양%장삭%강덕선%번동승
肌萎缩侧索硬化%诱发电位,躯体感觉%疼痛感受器
肌萎縮側索硬化%誘髮電位,軀體感覺%疼痛感受器
기위축측색경화%유발전위,구체감각%동통감수기
Amyotrophic lateral sclerosis%Evoked potentials,somatosensory%Nociceptors
目的 研究肌萎缩侧索硬化患者痛觉诱发电位的特点,评估其痛觉通路的传导.方法 肌萎缩侧索硬化患者60例,取卧位,应用接触性热痛诱发电位刺激器,直径27 mm(面积573 mm2),加热速度70℃/s.于54.5℃应用可调节脉冲,刺激部位为手背、前臂的掌侧面、第7颈椎棘突处(C7).记录仪器:Keypoint.net仪器.记录点为Cz和Pz.同时进行躯体感觉诱发电位检测,记录其波形及潜伏期.并对60名健康对照者进行相应研究.结果 肌萎缩侧索硬化患者接触性热痛诱发电位波形无异常,潜伏期分别为:手背刺激(561.2±28.6)ms,前臂掌侧刺激(540.1±39.2)ms,C7刺激(512.7±31.4)ms,与健康对照组[(558.7±30.2)、(536.6±23.5)、(501.8±26.0)ms]比较差异均无统计学意义(t=4.23、4.51、3.74,P＞0.05).其躯体感觉诱发电位各波潜伏期、波间期均正常.结论 肌萎缩侧索硬化患者接触性热痛诱发电位正常,提示其痛觉通路正常.
目的 研究肌萎縮側索硬化患者痛覺誘髮電位的特點,評估其痛覺通路的傳導.方法 肌萎縮側索硬化患者60例,取臥位,應用接觸性熱痛誘髮電位刺激器,直徑27 mm(麵積573 mm2),加熱速度70℃/s.于54.5℃應用可調節脈遲,刺激部位為手揹、前臂的掌側麵、第7頸椎棘突處(C7).記錄儀器:Keypoint.net儀器.記錄點為Cz和Pz.同時進行軀體感覺誘髮電位檢測,記錄其波形及潛伏期.併對60名健康對照者進行相應研究.結果 肌萎縮側索硬化患者接觸性熱痛誘髮電位波形無異常,潛伏期分彆為:手揹刺激(561.2±28.6)ms,前臂掌側刺激(540.1±39.2)ms,C7刺激(512.7±31.4)ms,與健康對照組[(558.7±30.2)、(536.6±23.5)、(501.8±26.0)ms]比較差異均無統計學意義(t=4.23、4.51、3.74,P＞0.05).其軀體感覺誘髮電位各波潛伏期、波間期均正常.結論 肌萎縮側索硬化患者接觸性熱痛誘髮電位正常,提示其痛覺通路正常.
목적 연구기위축측색경화환자통각유발전위적특점,평고기통각통로적전도.방법 기위축측색경화환자60례,취와위,응용접촉성열통유발전위자격기,직경27 mm(면적573 mm2),가열속도70℃/s.우54.5℃응용가조절맥충,자격부위위수배、전비적장측면、제7경추극돌처(C7).기록의기:Keypoint.net의기.기록점위Cz화Pz.동시진행구체감각유발전위검측,기록기파형급잠복기.병대60명건강대조자진행상응연구.결과 기위축측색경화환자접촉성열통유발전위파형무이상,잠복기분별위:수배자격(561.2±28.6)ms,전비장측자격(540.1±39.2)ms,C7자격(512.7±31.4)ms,여건강대조조[(558.7±30.2)、(536.6±23.5)、(501.8±26.0)ms]비교차이균무통계학의의(t=4.23、4.51、3.74,P＞0.05).기구체감각유발전위각파잠복기、파간기균정상.결론 기위축측색경화환자접촉성열통유발전위정상,제시기통각통로정상.
Objective To study the features of pain evoked potentials in patients with amyotrophic lateral sclemsis(ALS)and evaluate the pain pathway in these patients.Methods Sixty patients with ALS and 60 controls were set on supine position.The contact heat evoked potential stimulator with a diameter of 27 mm and an area of 573 mm2was used to elicit pain and contact heat evoked potentials(CHEP)in an accelerating speed of 70 ℃/s.Thermal stimuli were given at 54.5 ℃ to three body sites:the dorsum of hand,proximal volar for aml and C7. CHEP was recorded at spots of Cz and Pz.The features of CHEP was observed At the same time,somatosensory evoked potential(SEP)was assesed.Results The figure and latency of CHEP in ALS patients were normal.The latency was:the dorsum of hand:(561.2±28.6)ms; proximal volar forarm:(540.1±39.2)ms;C7:(512.7±31.4)ms.There were no significant differences of latency and SEP between tlle ALS patients and the controls((558.7±30.2),(536.6±23.5), (501.8±26.0)ms,t=4.23,4.51,3.74,P＞0.05).Conclusion Patients with ALS have a normal CHEP,suggesting that the pain pathway in patient with ALS is intact.
