CAJ | 학술논문

目的探讨64层CT血管造影(CTA)对颈动脉斑块检查的临床价值.方法分析2008年1月至8月我院116例颈动脉粥样硬化患者的CTA资料.结果共发现377个斑块,其中斑块钙化率63.加%;颈动脉斑块多见于颈总动脉(27.85%)、颈动脉分叉部(39.78%)及颈内动脉(21.48%).轻度与中度及重度狭窄组斑块构成的差异有统计学意义(P=0.000).≤50岁与≥70岁组间斑块类型差异有统计学意义(P=0.005).颈总动脉发生斑块的类型与颈动脉分叉部及颈内动脉间差异有统计学意义(P=0.000).逐步回归分析显示血管闭塞与临床症状正相关(B=1.080,P<0.05),而钙化性斑块与临床症状负相关(B=-0.688,P<0.05).结论 64层CTA不仅可评价颈动脉斑块的影像特征,还可定量测量血管狭窄;联合评价斑块类型、狭窄程度及发生的血管节段可对临床脑血管事件作出预测.
목적 탐토64층CT혈관조영(CTA)대경동맥반괴검사적림상개치.방법 분석2008년1월지8월아원116례경동맥죽양경화환자적CTA자료.결과 공발현377개반괴,기중반괴개화솔63.가%;경동맥반괴다견우경총동맥(27.85%)、경동맥분차부(39.78%)급경내동맥(21.48%).경도여중도급중도협착조반괴구성적차이유통계학의의(P=0.000).≤50세여≥70세조간반괴류형차이유통계학의의(P=0.005).경총동맥발생반괴적류형여경동맥분차부급경내동맥간차이유통계학의의(P=0.000).축보회귀분석현시혈관폐새여림상증상정상관(B=1.080,P<0.05),이개화성반괴여림상증상부상관(B=-0.688,P<0.05).결론 64층CTA불부가평개경동맥반괴적영상특정,환가정량측량혈관협착;연합평개반괴류형、협착정도급발생적혈관절단가대림상뇌혈관사건작출예측.
Objective To explore clinical significance of muhidetector(64-row)computed tomography carotid atherosclerosis angiography(MDCTA)in detecting carotid atherosclerotic plaque.Methods Data of 116 patients with carotid atherosclerosis undergone with MDCTA stayed at Huashan Hospital,Shanghai from January to August,2008 were analyzed retrospectively.Results Three hundred and seventy-seven plaques were identified among all the 116 patients in the study,with an incidence of calcified plaque of 63.40 percent,and more detected at the common carotid artery(27.85%).the carotid bifurcation(39.78%)and the internal carotid artery (21.48%).There was significantly statistical difference in plaque types between those with mild,moderate and severe carotid stenosis(P=0.000)and between those aged equal to or lower than 50 years and equal to or greater than 70 years(P=0.005).Plaque types at the common carotid artery were significantly difierent from those at the carotid bifurcation(P=0.000)and at the internal carotid artery(P=0.000).Results of regression analysis showed a positive and significant association between carotid occlusion and clinical symptomatology(with a coefficient of correlation of 1.080.P=0.023)and inverse association between calcified plaque and clinical symptomatology(with a coefficient of correlation of 0.688,P=0.006).Conclusions Not only imaging characteristics of carotid atherosclerotic plaque can be accurately assessed by MDCTA,but also measurement of its stenosis degree.Assessment of plaque type,degree of stenosis and distribution of plaque in different Vascular segments with MDCTA can be used to predict clinical occurrence of cerebevaseular events in patients with carotid atherosclerosis.