中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
16期
2423-2424
,共2页
苏芬太尼%芬太尼%镇痛,病人控制
囌芬太尼%芬太尼%鎮痛,病人控製
소분태니%분태니%진통,병인공제
Sufentanil%Fentanyl%Analgesia,patient-controlled
目的 比较苏芬太尼与芬太尼用于术后患者自控镇痛的临床疗效.方法 60例ASA Ⅰ～Ⅱ级择期腹部手术患者随机分为两组,每组30例.两组麻醉诱导和用药方式相同,手术结束时均给予芬太尼0.02 mg和氟哌利多1.5 mg静脉注射.然后行患者自控静脉镇痛(PCIA),苏芬太尼组与芬太尼组分别给予苏芬太尼0.1 mg和芬太尼1.0 mg,以0.9％氯化钠注射液稀释至100 ml,静脉泵入.观察术后48 h内两组VAS评分、镇静评分以及不良反应.结果 苏芬太尼组术后4、8h的VAS评分为低于芬大尼组(均P＜0.05),镇静评分高于芬太尼组(均P＜0.05).两组患者PCIA按压次数、不良反应发生率差异无统计学意义(均P＞0.05).结论 苏芬太尼与等效剂量芬太尼相比,镇痛作用更加完善,镇静作用强于芬太尼,用于术后静脉镇痛安全、有效.
目的 比較囌芬太尼與芬太尼用于術後患者自控鎮痛的臨床療效.方法 60例ASA Ⅰ～Ⅱ級擇期腹部手術患者隨機分為兩組,每組30例.兩組痳醉誘導和用藥方式相同,手術結束時均給予芬太尼0.02 mg和氟哌利多1.5 mg靜脈註射.然後行患者自控靜脈鎮痛(PCIA),囌芬太尼組與芬太尼組分彆給予囌芬太尼0.1 mg和芬太尼1.0 mg,以0.9％氯化鈉註射液稀釋至100 ml,靜脈泵入.觀察術後48 h內兩組VAS評分、鎮靜評分以及不良反應.結果 囌芬太尼組術後4、8h的VAS評分為低于芬大尼組(均P＜0.05),鎮靜評分高于芬太尼組(均P＜0.05).兩組患者PCIA按壓次數、不良反應髮生率差異無統計學意義(均P＞0.05).結論 囌芬太尼與等效劑量芬太尼相比,鎮痛作用更加完善,鎮靜作用彊于芬太尼,用于術後靜脈鎮痛安全、有效.
목적 비교소분태니여분태니용우술후환자자공진통적림상료효.방법 60례ASA Ⅰ～Ⅱ급택기복부수술환자수궤분위량조,매조30례.량조마취유도화용약방식상동,수술결속시균급여분태니0.02 mg화불고리다1.5 mg정맥주사.연후행환자자공정맥진통(PCIA),소분태니조여분태니조분별급여소분태니0.1 mg화분태니1.0 mg,이0.9％록화납주사액희석지100 ml,정맥빙입.관찰술후48 h내량조VAS평분、진정평분이급불량반응.결과 소분태니조술후4、8h적VAS평분위저우분대니조(균P＜0.05),진정평분고우분태니조(균P＜0.05).량조환자PCIA안압차수、불량반응발생솔차이무통계학의의(균P＞0.05).결론 소분태니여등효제량분태니상비,진통작용경가완선,진정작용강우분태니,용우술후정맥진통안전、유효.
Objective To compare the efficacy of sufentanil and fentanyl on patients with conteolled intravenous analgesia postoperatively.Methods A total of 60 ASA Ⅰ - Ⅱ patients underwent elective abdominal surgery were randomly divided into sufentanil group and fentanyl group( n =30 for each group).The loading dose for patient controlled intravenous analgesia(PCIA) in both groups was fentany1 0.02 mg and droperido1 1.5mg.Postoperative analgesia was obtained by a patient-controlled intravenous pump.Patients in the sufentanil group were received sufentanil 0.1mg with sodium chloride injection 100ml,and patients in the fentanyl group were received fentanyl 1.0mg with sodium chloride injection 100ml.The visual analog scale ( VAS),Ramsay scale,patient satisfaction and adverse reactions were investigated 48h after operation.Results VAS scores at 4,8h after operation in the sufentanil group were lower than those in the fentanyl group(all P ＜0.05).Ramsay scale scores in the sufentanil group were higher than those in the fentanyl group( all P ＜0.05 ).There were no significant differences in PCIA pressing times and adverse reactions between the two groups ( all P ＞ 0.05 ).Conclusion Intravenous postoperative analgesia with sufentanil had better analgesic effect and stronger sedation effect than equivalent dose of fentanyl.
