中华航空航天医学杂志
中華航空航天醫學雜誌
중화항공항천의학잡지
CHINESE JOURNAL OF AEROSPACE MEDICINE
2010年
1期
51-55
,共5页
邓昌磊%肖华军%臧斌%付丽珊%顾昭%王桂友
鄧昌磊%肖華軍%臧斌%付麗珊%顧昭%王桂友
산창뢰%초화군%장빈%부려산%고소%왕계우
高海拔%缺氧%睡眠%心率%富氧室
高海拔%缺氧%睡眠%心率%富氧室
고해발%결양%수면%심솔%부양실
Altitude%Anoxia%Sleep%Heart rate%Oxygen-enriched room
目的 通过研究高原人工富氧环境(简称富氧室)对急进高原人员睡眠的作用,探讨富氧室的抗缺氧效果及其与高原习服的关系. 方法 利用分子筛制氧机在海拔3500 m高原建立富氧室.将18名世居平原人员随机分为富氧组、缺氧组和平原组,每组各6人.平原组不进入高原,富氧组和缺氧组人员乘飞机到达高原后,在未供氧情况下记录2组受试人员的心率和血氧饱和度(arterial oxygen saturation,SaO2).当晚22:00两组人员分别进入富氧室和普通房间,休息至次日上午9:00通过睡眠呼吸记录分析系统,对受试人员进行监测,在同一时间对平原组也进行监测.数据采集完毕后利用系统自带分析软件进行分析. 结果 ①富氧组供氧后SaO2为92.3%.±1.0%,高于供氧前的82.9%±4.2%和缺氧组的79.3%±5.9%(P<0.01),但低于平原组的97.3%±0.8%(P<0.05),且差异均有统计学意义.心率值在富氧组供氧前后及与缺氧组间差异无统计学意义,但均高于平原组,且差异有统计学意义(P<0.01).②睡眠结构富氧组与缺氧组差异无统计学意义,与平原组比较浅睡眠偏多,深睡眠偏少,且差异有统计学意义(P<0.01).低通气次数和呼吸紊乱指数平原组低于缺氧组和富氧组(P<0.01);富氧组呼吸紊乱指数低于缺氧组,两组分别为28.1±11.9和53.2±23.4,且差异有统计学意义(P<0.05).③睡眠期间,富氧组和缺氧组的归一化低频功率和低频与高频的比值分别为89.3±2.9、9.4±2.8和90.2±1.8、9.9±1.9,组间差异无统计学意义,但均高于平原组的85.8±2.9和6.4±1.4,且差异有统计学意义(P<0.05);平原组的归一化高频功率则高于富氧组和缺氧组,且差异有统计学意义(P<0.05). 结论 高原富氧室可以有效改善急进高原人员睡眠情况,但对睡眠期间心率变异性未见显著影响,且与高原习服的关系尚待深入研究.
目的 通過研究高原人工富氧環境(簡稱富氧室)對急進高原人員睡眠的作用,探討富氧室的抗缺氧效果及其與高原習服的關繫. 方法 利用分子篩製氧機在海拔3500 m高原建立富氧室.將18名世居平原人員隨機分為富氧組、缺氧組和平原組,每組各6人.平原組不進入高原,富氧組和缺氧組人員乘飛機到達高原後,在未供氧情況下記錄2組受試人員的心率和血氧飽和度(arterial oxygen saturation,SaO2).噹晚22:00兩組人員分彆進入富氧室和普通房間,休息至次日上午9:00通過睡眠呼吸記錄分析繫統,對受試人員進行鑑測,在同一時間對平原組也進行鑑測.數據採集完畢後利用繫統自帶分析軟件進行分析. 結果 ①富氧組供氧後SaO2為92.3%.±1.0%,高于供氧前的82.9%±4.2%和缺氧組的79.3%±5.9%(P<0.01),但低于平原組的97.3%±0.8%(P<0.05),且差異均有統計學意義.心率值在富氧組供氧前後及與缺氧組間差異無統計學意義,但均高于平原組,且差異有統計學意義(P<0.01).②睡眠結構富氧組與缺氧組差異無統計學意義,與平原組比較淺睡眠偏多,深睡眠偏少,且差異有統計學意義(P<0.01).低通氣次數和呼吸紊亂指數平原組低于缺氧組和富氧組(P<0.01);富氧組呼吸紊亂指數低于缺氧組,兩組分彆為28.1±11.9和53.2±23.4,且差異有統計學意義(P<0.05).③睡眠期間,富氧組和缺氧組的歸一化低頻功率和低頻與高頻的比值分彆為89.3±2.9、9.4±2.8和90.2±1.8、9.9±1.9,組間差異無統計學意義,但均高于平原組的85.8±2.9和6.4±1.4,且差異有統計學意義(P<0.05);平原組的歸一化高頻功率則高于富氧組和缺氧組,且差異有統計學意義(P<0.05). 結論 高原富氧室可以有效改善急進高原人員睡眠情況,但對睡眠期間心率變異性未見顯著影響,且與高原習服的關繫尚待深入研究.
목적 통과연구고원인공부양배경(간칭부양실)대급진고원인원수면적작용,탐토부양실적항결양효과급기여고원습복적관계. 방법 이용분자사제양궤재해발3500 m고원건립부양실.장18명세거평원인원수궤분위부양조、결양조화평원조,매조각6인.평원조불진입고원,부양조화결양조인원승비궤도체고원후,재미공양정황하기록2조수시인원적심솔화혈양포화도(arterial oxygen saturation,SaO2).당만22:00량조인원분별진입부양실화보통방간,휴식지차일상오9:00통과수면호흡기록분석계통,대수시인원진행감측,재동일시간대평원조야진행감측.수거채집완필후이용계통자대분석연건진행분석. 결과 ①부양조공양후SaO2위92.3%.±1.0%,고우공양전적82.9%±4.2%화결양조적79.3%±5.9%(P<0.01),단저우평원조적97.3%±0.8%(P<0.05),차차이균유통계학의의.심솔치재부양조공양전후급여결양조간차이무통계학의의,단균고우평원조,차차이유통계학의의(P<0.01).②수면결구부양조여결양조차이무통계학의의,여평원조비교천수면편다,심수면편소,차차이유통계학의의(P<0.01).저통기차수화호흡문란지수평원조저우결양조화부양조(P<0.01);부양조호흡문란지수저우결양조,량조분별위28.1±11.9화53.2±23.4,차차이유통계학의의(P<0.05).③수면기간,부양조화결양조적귀일화저빈공솔화저빈여고빈적비치분별위89.3±2.9、9.4±2.8화90.2±1.8、9.9±1.9,조간차이무통계학의의,단균고우평원조적85.8±2.9화6.4±1.4,차차이유통계학의의(P<0.05);평원조적귀일화고빈공솔칙고우부양조화결양조,차차이유통계학의의(P<0.05). 결론 고원부양실가이유효개선급진고원인원수면정황,단대수면기간심솔변이성미견현저영향,차여고원습복적관계상대심입연구.
Objective To study the effects of the artificial oxygen-enriched environment (is called "oxygen-enriched room" in short) on sleep efficiency of the people who participate in the mission on plateau with hurry-up entry,and to investigate the anti-hypoxia effect of oxygen-enriched room to plateau acclimatization. Methods Eighteen subjects were randomly and averagety allocated into plain group,oxygen-enriched group and hypoxia group.Only the later two groups were dispatched to plateau by air.Molecular sieve oxygenerator was used to supply the room with oxygen on 3500 m plateau.The oxygen-enriched group and hypoxia group got into the oxygen-enriched rooms and normal rooms respectively at 22 o' clock and took rest till to 9 o' clock next morning.The changes of heart rate (HR) and the saturation of blood oxygen (SaO2) of three groups were recorded and compared between the states of with and without oxygen enrichment.The subjects were monitored by sleep respiration recording and analysis system. Results ①The SaO2 of the oxygen-enriched group was 92.3%±1.0%,and it was significant higher than the state before oxygen enrichment (82.9%±4.2%) and than that of hypoxia group (79.3%±5.9%,P<0.01),but lower than that of plain group (97.3%±0.8%,P<0.05).②There were less deep sleep and more slight sleep in hypoxia group and oxygen-enriched group than in plain group.The hypopnea and apnea hypopnea index (AHI) of plain group was significant lower than that of hypoxia group and oxygen-enriched group (P<0.05).The AHI of the oxygen-enriched group was 28.1±11.9,and it was significant lower than that of hypoxia group (53.2±23.4)(P<0.05).③The normalized low-frequency (Ln) and the ratio of low-frequency to high-frequency (LF/HF) measured in sleep was respectively 89.3±2.9 and 6.4±1.4 in oxygen-enriched group comparing to 90.2±1.8 and 9.9±1.9 in hypoxia group but without statistical difference.The corresponding Ln and LF/HF of plain group was 85.8±2.9 and 6.4±1.4 respectively,significantly higher than those of other two groups (P<0.05).Plain group also showed higher normalized high-frequency than others(P<0.05). Conclusions Oxygen-enriched environment can effectively improve the sleep quality but significantly change heart rate variation (HRV) of the people who participate in the mission with hurry-up entry to plateau.Further studies are still needed to reveal the quantitative effectiveness of oxygen-enriched room to plateau acclimatization.
