K-ras基因在人喉鳞状细胞癌细胞株(Hep-2)中的表达及其意义
K-ras기인재인후린상세포암세포주(Hep-2)중적표체급기의의
Relation between the Expression of K-ras in Hep-2 Cells and Development of Laryngeal Carcinoma
  • 万方数据
    中德临床肿瘤学杂志(英文版) 중덕림상종류학잡지(영문판)
    THE CHINESE-GERMAN JOURNAL OF CLINICAL ONCOLOGY
    2006年 1期 18-19 ,共2页

    陈雄%孔维佳%张苏琳%张丹

    진웅%공유가%장소림%장단



    K-ras%human laryngeal squamous cell carcinoma cell lines (Hep-2)%RT-PCR


    Objective: To investigate the expression of K-ras in human laryngeal squamous cell carcinoma cell lines (Hep-2) and its significance for establishing a solid foundation for further study of the relationship between human laryngeal squamous cell carcinoma and K-ras gene point mutations. Methods:The expression of K-ras in human laryngeal squamous cell carcinoma cell lines (Hep-2) and human pancreatic carcinoma cell lines (MIAPaCa-2) was detected by using RT-PCR. Results: The expression of K-ras mRNA in Hep-2 and MIAPaCa-2 was strong and positive. Conclusion: The expression of K-rasmRNA in human laryngeal squamous cell carcinoma cell lines (Hep-2) is positive. Development of laryngeal carcinoma might be related to the activation of K-ras gene point mutation.
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