中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2009年
34期
21-23
,共3页
脂肪组织%网膜素%冠状动脉疾病
脂肪組織%網膜素%冠狀動脈疾病
지방조직%망막소%관상동맥질병
Adipose tissue%Omentin%Coronary disease
目的 探讨血浆网膜素水平与冠心病的关系.方法 选择2008年4-9月住院的患者88例,分为冠心病组56例(其中急性冠脉综合征28例,稳定型心绞痛28例)和非冠心病组32例.分别于入院次日空腹经肘静脉抽取静脉血,使用ELISA法测定血浆网膜素水平,并测量身高、体重、血压、总胆同醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、三酰甘油、高敏C反应蛋白.结果 冠心病组血浆网膜素水平较非冠心病组低[(33.4±6.4)μg/L(51.8±7.7)μg/L],差异有统计学意义(P=0.034).多因素Logistic回归分析显示,血浆网膜素水平下降为冠心病的独立危险因素(P=0.012).结论 血浆网膜素水平下降是冠心病的独立危险因素.血浆网膜素可能在冠心病的发病机制中起到一定作用.
目的 探討血漿網膜素水平與冠心病的關繫.方法 選擇2008年4-9月住院的患者88例,分為冠心病組56例(其中急性冠脈綜閤徵28例,穩定型心絞痛28例)和非冠心病組32例.分彆于入院次日空腹經肘靜脈抽取靜脈血,使用ELISA法測定血漿網膜素水平,併測量身高、體重、血壓、總膽同醇、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇、三酰甘油、高敏C反應蛋白.結果 冠心病組血漿網膜素水平較非冠心病組低[(33.4±6.4)μg/L(51.8±7.7)μg/L],差異有統計學意義(P=0.034).多因素Logistic迴歸分析顯示,血漿網膜素水平下降為冠心病的獨立危險因素(P=0.012).結論 血漿網膜素水平下降是冠心病的獨立危險因素.血漿網膜素可能在冠心病的髮病機製中起到一定作用.
목적 탐토혈장망막소수평여관심병적관계.방법 선택2008년4-9월주원적환자88례,분위관심병조56례(기중급성관맥종합정28례,은정형심교통28례)화비관심병조32례.분별우입원차일공복경주정맥추취정맥혈,사용ELISA법측정혈장망막소수평,병측량신고、체중、혈압、총담동순、고밀도지단백담고순、저밀도지단백담고순、삼선감유、고민C반응단백.결과 관심병조혈장망막소수평교비관심병조저[(33.4±6.4)μg/L(51.8±7.7)μg/L],차이유통계학의의(P=0.034).다인소Logistic회귀분석현시,혈장망막소수평하강위관심병적독립위험인소(P=0.012).결론 혈장망막소수평하강시관심병적독립위험인소.혈장망막소가능재관심병적발병궤제중기도일정작용.
Objective To investigate the relation between omentin and coronary artery disease.Methods Eighty-eight eases were divided into 2 groups, coronary artery disease group (56 cases, includingacute coronary syndrome 28 cases and stable angina 28 cases), and non-coronary artery disease group (32cases). The plasma omentin levels were assayed by ELISA, and height, weight, blood pressure, totalcholesterol high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C),lriglyeeride (TG), high-sensitivity C-reactive protein were detected. Results The plasma omentin level incoronary artery disease group [(33.4 + 6.4) μg/L] was lower than that in non-coronary artery disease group [(51.8 + 7.7) μg/L](P= 0.034). Logistic analysis showed that the decline of omentin was an independent risk factor of coronary artery disease (P=0.012). Conclusions The decline of omentin is an independent risk factor of coronary artery disease. The plasma omentin may contribute, in part, to the pathogenesis of coronary artery disease.