中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2012年
5期
454-457
,共4页
陈青山%李志%余宝花%谢秀英%曾键%古洵清
陳青山%李誌%餘寶花%謝秀英%曾鍵%古洵清
진청산%리지%여보화%사수영%증건%고순청
脉络膜疾病/分类%脉络膜疾病/诊断%吲哚花青绿/诊断应用
脈絡膜疾病/分類%脈絡膜疾病/診斷%吲哚花青綠/診斷應用
맥락막질병/분류%맥락막질병/진단%신타화청록/진단응용
Choroid diseases/classification%Choroid diseases/diagnosis%Indocyanine green/diagnostic use
目的 了解不同类型息肉样脉络膜血管病变(PCV)患者视力改变情况.方法 收集经眼底彩色照相、荧光素眼底血管造影、吲哚青绿血管造影(ICGA)以及光相干断层扫描检查确诊的67例PCV患者68只眼的临床资料.根据PCV的活动性与病理特征分为静止性、渗出性和出血性PCV;根据ICGA检查中息肉样病灶的形态特征以及是否合并分支状脉络膜血管网(BVN)分为葡萄状病灶型、单个病灶型和合并BVN的混合病灶型PCV;根据息肉样病灶分布部位分为黄斑区、血管弓区、视盘旁区、中周部和混合区PCV.观察各组的视力情况.结果 静止性、渗出性、少量出血性、多量出血性PCV分别有16、19、19、14只眼,其平均最小分辨角对数(logMAR)视力分别为0.34±0.52、0.70±0.98、0.60±0.50、0.91±0.75.静止性PCV患眼平均视力显著优于渗出性、少量出血性与多量出血性PCV患眼,组间比较,差异有统计学意义(q＝4.75、4.26、5.13,P＜0.05).渗出性PCV与少量出血性PCV患眼平均视力比较,差异没有统计学意义(q=0.98,P＞0.05).葡萄状病灶型、单个病灶或多处单个病灶型、合并BVN的混合病灶型PCV分别有22、38、8只眼,其平均logMAR视力分别为0.52±0.55、0.59±0.43、0.80±0.95.伴有BVN的混合病灶型PCV患眼平均视力显著差于葡萄状病灶型和单个病灶或多处单个病灶型PCV患眼,组间比较,差异有统计学意义(q=3.81、3.02,P＜0.05).黄斑区、血管弓区、视盘旁区、混合区PCV分别有34、1 3、8、13只眼,其平均logMAR视力分别为0.78±0.43、0.57±0.37、0.38±0.27、0.74±0.41.黄斑区PCV患眼平均视力差于血管弓区与视盘旁区PCV患眼,组间比较,差异有统计学意义(q=4.61、5.11,P＜0.05);黄斑区PCV与混合区PCV患眼平均视力比较,差异无统计学意义(q=0.73,P＞0.05).结论 PCV患者视力改变情况不一,且与PCV的活动性与病理特征、息肉样病灶的形态特征和分布部位以及是否合并BVN有关.
目的 瞭解不同類型息肉樣脈絡膜血管病變(PCV)患者視力改變情況.方法 收集經眼底綵色照相、熒光素眼底血管造影、吲哚青綠血管造影(ICGA)以及光相榦斷層掃描檢查確診的67例PCV患者68隻眼的臨床資料.根據PCV的活動性與病理特徵分為靜止性、滲齣性和齣血性PCV;根據ICGA檢查中息肉樣病竈的形態特徵以及是否閤併分支狀脈絡膜血管網(BVN)分為葡萄狀病竈型、單箇病竈型和閤併BVN的混閤病竈型PCV;根據息肉樣病竈分佈部位分為黃斑區、血管弓區、視盤徬區、中週部和混閤區PCV.觀察各組的視力情況.結果 靜止性、滲齣性、少量齣血性、多量齣血性PCV分彆有16、19、19、14隻眼,其平均最小分辨角對數(logMAR)視力分彆為0.34±0.52、0.70±0.98、0.60±0.50、0.91±0.75.靜止性PCV患眼平均視力顯著優于滲齣性、少量齣血性與多量齣血性PCV患眼,組間比較,差異有統計學意義(q＝4.75、4.26、5.13,P＜0.05).滲齣性PCV與少量齣血性PCV患眼平均視力比較,差異沒有統計學意義(q=0.98,P＞0.05).葡萄狀病竈型、單箇病竈或多處單箇病竈型、閤併BVN的混閤病竈型PCV分彆有22、38、8隻眼,其平均logMAR視力分彆為0.52±0.55、0.59±0.43、0.80±0.95.伴有BVN的混閤病竈型PCV患眼平均視力顯著差于葡萄狀病竈型和單箇病竈或多處單箇病竈型PCV患眼,組間比較,差異有統計學意義(q=3.81、3.02,P＜0.05).黃斑區、血管弓區、視盤徬區、混閤區PCV分彆有34、1 3、8、13隻眼,其平均logMAR視力分彆為0.78±0.43、0.57±0.37、0.38±0.27、0.74±0.41.黃斑區PCV患眼平均視力差于血管弓區與視盤徬區PCV患眼,組間比較,差異有統計學意義(q=4.61、5.11,P＜0.05);黃斑區PCV與混閤區PCV患眼平均視力比較,差異無統計學意義(q=0.73,P＞0.05).結論 PCV患者視力改變情況不一,且與PCV的活動性與病理特徵、息肉樣病竈的形態特徵和分佈部位以及是否閤併BVN有關.
목적 료해불동류형식육양맥락막혈관병변(PCV)환자시력개변정황.방법 수집경안저채색조상、형광소안저혈관조영、신타청록혈관조영(ICGA)이급광상간단층소묘검사학진적67례PCV환자68지안적림상자료.근거PCV적활동성여병리특정분위정지성、삼출성화출혈성PCV;근거ICGA검사중식육양병조적형태특정이급시부합병분지상맥락막혈관망(BVN)분위포도상병조형、단개병조형화합병BVN적혼합병조형PCV;근거식육양병조분포부위분위황반구、혈관궁구、시반방구、중주부화혼합구PCV.관찰각조적시력정황.결과 정지성、삼출성、소량출혈성、다량출혈성PCV분별유16、19、19、14지안,기평균최소분변각대수(logMAR)시력분별위0.34±0.52、0.70±0.98、0.60±0.50、0.91±0.75.정지성PCV환안평균시력현저우우삼출성、소량출혈성여다량출혈성PCV환안,조간비교,차이유통계학의의(q＝4.75、4.26、5.13,P＜0.05).삼출성PCV여소량출혈성PCV환안평균시력비교,차이몰유통계학의의(q=0.98,P＞0.05).포도상병조형、단개병조혹다처단개병조형、합병BVN적혼합병조형PCV분별유22、38、8지안,기평균logMAR시력분별위0.52±0.55、0.59±0.43、0.80±0.95.반유BVN적혼합병조형PCV환안평균시력현저차우포도상병조형화단개병조혹다처단개병조형PCV환안,조간비교,차이유통계학의의(q=3.81、3.02,P＜0.05).황반구、혈관궁구、시반방구、혼합구PCV분별유34、1 3、8、13지안,기평균logMAR시력분별위0.78±0.43、0.57±0.37、0.38±0.27、0.74±0.41.황반구PCV환안평균시력차우혈관궁구여시반방구PCV환안,조간비교,차이유통계학의의(q=4.61、5.11,P＜0.05);황반구PCV여혼합구PCV환안평균시력비교,차이무통계학의의(q=0.73,P＞0.05).결론 PCV환자시력개변정황불일,차여PCV적활동성여병리특정、식육양병조적형태특정화분포부위이급시부합병BVN유관.
Objective To observe the prognosis of visual acuity (VA) of patients with different classification of polypoidal choroidal vasculopathy (PCV).Methods Sixty-seven PCV patients (68 eyes) diagnosed by fundus photography,fundus fluorescein angiography,indocyanine green angiography (ICGA)and ocular coherence tomography were enrolled in this retrospective study.The patients were classified into static,exudative,small hemorrhage and large hemorrhage according to activity and pathological characteristics of lesions.The patients were classified into aciniform,single or several single,combined branching choroidal vascular network (BVN) according to morphological characteristics and combination with BVN of lesions on ICGA.The patients also were classified into macular,vascular arcade,peripapillary and mixing zone according to distribution of lesions.The VA of all the types were observed.Results There were 16,19,19,14 eyes in the type of static,exudative,small hemorrhage and large hemorrhage PCV,which with logMAR VA of 0.34±0.52,0.70±0.98,0.60±0.50,0.91±0.75 respectively.The VA of static PCV patients was better than that in exudative,small hemorrhage and large hemorrhage PCV patients (q=4.75,4.26,5.13; P＜0.05).There was no significant difference of VA between exudative and small hemorrhage PCV patients (q=0.98,P＞0.05).There were 22,38 and eight eyes in the type of aciniform,single or several single,combined BVN PCV,which with logMAR VA of 0.52 ± 0.55,0.59 ± 0.43,0.80±0.95 respectively.The VA of combined BVN PCV patients was worse than that in aciniform and single or several single PCV patients (q＝3.81,3.02 ; P＜0.05 ).There were 34,13,8 and 13 eyes in the type of macular,vascular arcade,peripapillary and mixing zone PCV,which with logMAR VA of 0.78±0.43.0.5±0.37,0.38±0.27,0.74±0.41 respectively.The VA of macular PCV patients was less than that in vascular arcade and peripapillary PCV patients (q=4.61,5.11;P＜0.05).There was no significant difference of VA between macula and mixing zone PCV patients (q=0.73,P＞0.05).Conclusions The VA of PCV patients is variable.It is related to activity and pathological characteristics of lesions,morphological characteristics and combination with BVN of lesions on ICGA,and distribution of lesions.
