中华心律失常学杂志
中華心律失常學雜誌
중화심률실상학잡지
CHINESE JOURNAL OF CARDIAC ARRHYTHMIAS
2011年
6期
421-425
,共5页
张逸杰%包明威%谭团团%夏豪%周纪宁%杨剑雪%王芳%哈飞%黄从新
張逸傑%包明威%譚糰糰%夏豪%週紀寧%楊劍雪%王芳%哈飛%黃從新
장일걸%포명위%담단단%하호%주기저%양검설%왕방%합비%황종신
运动平板试验%冠心病%复极
運動平闆試驗%冠心病%複極
운동평판시험%관심병%복겁
Treadmill exercise test%Coronary heart disease%Repolarization
目的 观察冠心病患者在平板运动负荷试验中的QT间期滞后现象.方法 收集21例经冠状动脉造影确诊的冠心病患者(冠心病组)和20例健康志愿者(对照组).分析两组的平板运动负荷试验心电图,每份心电图测量50个点的RR间期、QTp间期(Q波起始到T波顶峰的时间)和QTe间期(Q波起始到T波终末的时间),采用Bazett公式[QTc=QT/(RR)1/2]计算QTpc间期及QTec间期.以RR间期为横坐标,QTp间期、QTe间期、QTpc间期或QTec间期为纵坐标,作散点图及曲线.比较RR间期为600、550、500、450、400 ms时,运动期QTp间期、QTe间期、QTpc间期或QTec间期与恢复期的差异.结果 对照组运动期和恢复期的QT/RR曲线几乎重叠；冠心病组运动期和恢复期的QT/RR曲线在RR间期500～600 ms段明显分离,恢复期低于运动期.对照组在各RR间期下,运动期QT间期和QTc间期与恢复期的差异无统计学意义(P＞0.05).冠心病组在RR间期为550、500、450 ms时,运动期QTp间期和QTpc间期显著高于恢复期(P＜0.05)；在RR间期为550、500 ms时,运动期QTe间期和QTec间期显著高于恢复期(P＜0.05).结论 冠心病患者在平板运动负荷试验中有明显的QT滞后现象,后者可能在冠心病的早期无创检测中发挥一定作用.
目的 觀察冠心病患者在平闆運動負荷試驗中的QT間期滯後現象.方法 收集21例經冠狀動脈造影確診的冠心病患者(冠心病組)和20例健康誌願者(對照組).分析兩組的平闆運動負荷試驗心電圖,每份心電圖測量50箇點的RR間期、QTp間期(Q波起始到T波頂峰的時間)和QTe間期(Q波起始到T波終末的時間),採用Bazett公式[QTc=QT/(RR)1/2]計算QTpc間期及QTec間期.以RR間期為橫坐標,QTp間期、QTe間期、QTpc間期或QTec間期為縱坐標,作散點圖及麯線.比較RR間期為600、550、500、450、400 ms時,運動期QTp間期、QTe間期、QTpc間期或QTec間期與恢複期的差異.結果 對照組運動期和恢複期的QT/RR麯線幾乎重疊；冠心病組運動期和恢複期的QT/RR麯線在RR間期500～600 ms段明顯分離,恢複期低于運動期.對照組在各RR間期下,運動期QT間期和QTc間期與恢複期的差異無統計學意義(P＞0.05).冠心病組在RR間期為550、500、450 ms時,運動期QTp間期和QTpc間期顯著高于恢複期(P＜0.05)；在RR間期為550、500 ms時,運動期QTe間期和QTec間期顯著高于恢複期(P＜0.05).結論 冠心病患者在平闆運動負荷試驗中有明顯的QT滯後現象,後者可能在冠心病的早期無創檢測中髮揮一定作用.
목적 관찰관심병환자재평판운동부하시험중적QT간기체후현상.방법 수집21례경관상동맥조영학진적관심병환자(관심병조)화20례건강지원자(대조조).분석량조적평판운동부하시험심전도,매빈심전도측량50개점적RR간기、QTp간기(Q파기시도T파정봉적시간)화QTe간기(Q파기시도T파종말적시간),채용Bazett공식[QTc=QT/(RR)1/2]계산QTpc간기급QTec간기.이RR간기위횡좌표,QTp간기、QTe간기、QTpc간기혹QTec간기위종좌표,작산점도급곡선.비교RR간기위600、550、500、450、400 ms시,운동기QTp간기、QTe간기、QTpc간기혹QTec간기여회복기적차이.결과 대조조운동기화회복기적QT/RR곡선궤호중첩；관심병조운동기화회복기적QT/RR곡선재RR간기500～600 ms단명현분리,회복기저우운동기.대조조재각RR간기하,운동기QT간기화QTc간기여회복기적차이무통계학의의(P＞0.05).관심병조재RR간기위550、500、450 ms시,운동기QTp간기화QTpc간기현저고우회복기(P＜0.05)；재RR간기위550、500 ms시,운동기QTe간기화QTec간기현저고우회복기(P＜0.05).결론 관심병환자재평판운동부하시험중유명현적QT체후현상,후자가능재관심병적조기무창검측중발휘일정작용.
Objective To observe the QT interval hysteresis phenomenon in treadmill exercise testing in patients with coronary heart disease (CHD).Methods Twenty-one patients with CHD,which were diagnosed based on their coronary artery angiography,were enrolled as CHD group.Twenty healthy people were enrolled as control group (con).All subjects underwent treadmill exercise test according to Bruce protocol For each recording,50 points were selected for the RR,QTp(from the onset of QRS to the peak of T wave),and QTe(from the onset of QRS to the end of T wave)interval measurement.Rate corrected QTp(QTpc) and QTe (QTec) were calculated using Bazett formula[ QTc =QT/( RR ) 1/2 ].QTp,QTe,QTpc and QTec interval were plotted against corresponding RR interval,respectively.The difference in QTp,QTe,QTpc and QTec were compared between exercise and recovery period,under RR interval of 600 ms,550 ms,500 ms,450 ms,and 400ms.Results In control group,the QT/RR curve of recovery period nearly overlapped with exercise period.In CHD group,the QT/RR curve of recovery period separated downward from exercise period at the region of RR interval from 500 ms to 600 ms.In control group,there were no significant difference in QTp,QTe,QTpc and QTec between exercise and recovery period under any same RR interval ( P＞0.05 ).In CHD group,QTp and QTpc of exercise period was significant higher than that in recovery period under RR interval of 550 ms,500 ms,and 450 ms( P＜0.05 ),QTe and QTec of exercise period was significant higher than that in recovery period under RR interval of 550 ms,and 500 ms(P＜0.05).Conclusion In treadmill exercise testing,patients with CHD showed overt QT interval hysteresis phenomenon.The QT hysteresis might serve as a useful non-invasive tool in the early detection of patients with CHD.
