CAJ | 학술논문

目的采用自适应光学技术分析实时动态矫正单项高阶像差对视力的影响.方法对照研究.在暗室中,对12位年轻健康志愿者给予右眼5 g/L盐酸去氧肾上腺素散瞳,使瞳孔直径达到6.0mm以上.通过光学镜片对受试者的近视和散光充分矫正,利用自适应光学系统进行彗差、三叶草像差、球差和球差外4阶像差等不同单项高阶像差的矫正,同时进行100％对比度视力的检测.采用配对t检验来分析不同矫正策略之间的视力差异和像差RMS值差异.结果不同单项高阶像差均被彻底矫正,其余像差保持不变.矫正彗差、三叶草像差、球差和球差外4阶像差后,受试者的视力分别平均提高了0.021 LogMAR、0.017 LogMAR、0.022 LogMAR和0.025 LogMAR,视力变化率分别为(-0.40±1.22)LogMAR/μm、(-0.20±0.61)LogMAR/μM、(-0.80±1.44)LogMAR/μm和(-0.30±0.57)LogMAR/μm.不同单项高阶像差矫正下的视力和残余像差均方根值呈线性关系(R2=0.13,P＜0.01).结论在正常人眼高阶像差中,球差对视力的影响程度最大,其次是彗差、球差外4阶像差和三叶草像差,视力的变化和残余像差均方根值呈线性相关.
목적 채용자괄응광학기술분석실시동태교정단항고계상차대시력적영향.방법 대조연구.재암실중,대12위년경건강지원자급여우안5 g/L염산거양신상선소산동,사동공직경체도6.0mm이상.통과광학경편대수시자적근시화산광충분교정,이용자괄응광학계통진행혜차、삼협초상차、구차화구차외4계상차등불동단항고계상차적교정,동시진행100％대비도시력적검측.채용배대t검험래분석불동교정책략지간적시력차이화상차RMS치차이.결과 불동단항고계상차균피철저교정,기여상차보지불변.교정혜차、삼협초상차、구차화구차외4계상차후,수시자적시력분별평균제고료0.021 LogMAR、0.017 LogMAR、0.022 LogMAR화0.025 LogMAR,시력변화솔분별위(-0.40±1.22)LogMAR/μm、(-0.20±0.61)LogMAR/μM、(-0.80±1.44)LogMAR/μm화(-0.30±0.57)LogMAR/μm.불동단항고계상차교정하적시력화잔여상차균방근치정선성관계(R2=0.13,P＜0.01).결론 재정상인안고계상차중,구차대시력적영향정도최대,기차시혜차、구차외4계상차화삼협초상차,시력적변화화잔여상차균방근치정선성상관.
Objective To analyze the effects of single mode's high-order aberration on visual acuity in real time dynamically corrected using adaptive optics technique.Methods Control study.In a dark room,twelve young healthy volunteers were administrated with 5 g/l phenylephedrine to fully dilate the right eye's pupil to a diameter over 6 mm.The subjects' myopia and astigmatism were fully corrected using optical lenses.Coma,trefoil,spherical aberration and other forth-order aberrations except for spherical aberration were corrected using adaptive optics,and 100％ contrast visual acuity was simultaneously measured.Results All single mode's high-order aberrations were fully corrected,whereas other aberrations remained unchanged.Mean visual acuity of subjects was improved by 0.021 LogMAR,0.017 LogMAR,0.022 LogMAR and 0.025 LogMAR after correction of coma,trefoil,spherical aberration and other forth-order aberrations except for spherical aberration,respectively.Ratio of change in visual acuity was ( - 0.40 ± 1.22) LogMAR/μm,( -0.20 +0.61) LogMAR/μm,( -0.80 + 1.44) LogMAR/μm and ( -0.30 ± 0.57) LogMAR/μm,respectively.There was a linear correlation between visual acuity after correction of single mode's different high-order aberrations and RMS of residual aberrations ( R2 =0.13,P ＜ 0.01 ).Conclusion Among high-order aberrations in normal human eye,spherical aberration generates a most impact on visual acuity,followed by coma,other forth-order aberrations except for spherical aberration and trefoil.A linear correlation was found between change in visual acuity and RMS of residual aberrations.