中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
8期
93-95
,共3页
DIC%vWF%PLT%凝血因子时间%临床意义
DIC%vWF%PLT%凝血因子時間%臨床意義
DIC%vWF%PLT%응혈인자시간%림상의의
DIC%vWF%PLT%Coagulation factor time%Clinical significance
目的 探讨vWF含量、PLT数量和凝血因子时间变化在DIC早期诊断中的临床价值.方法 血清vWF测定采用免疫比浊法,使用日本产OLYMPUSAU-400全自动生化分析仪测定;PT、APTT、TT、Fig测定采用凝固法,使用日本产sysmex CA-530凝血分析仪测定;PLT计数用EDTA-K2抗凝静脉血,使用日本产sysmex K-1000全自动血细胞计数仪测定.结果 DIC病例组血清vWF和Fig含量、PLT数量及PT、APTT、TT时间显著高于正常对照组,差异具有显著性意义(P＜0.01),并随着DIC的发展而逐步升高.结论 vWF含量、PLT数量和凝血因子时间变化,可以作为DIC早期预测、诊断的重要指标,而且其动态测定结果还可以作为监测DIC病情发展情况、评价疗效、判断疾病严重程度和估计预后的重要实验参数.
目的 探討vWF含量、PLT數量和凝血因子時間變化在DIC早期診斷中的臨床價值.方法 血清vWF測定採用免疫比濁法,使用日本產OLYMPUSAU-400全自動生化分析儀測定;PT、APTT、TT、Fig測定採用凝固法,使用日本產sysmex CA-530凝血分析儀測定;PLT計數用EDTA-K2抗凝靜脈血,使用日本產sysmex K-1000全自動血細胞計數儀測定.結果 DIC病例組血清vWF和Fig含量、PLT數量及PT、APTT、TT時間顯著高于正常對照組,差異具有顯著性意義(P＜0.01),併隨著DIC的髮展而逐步升高.結論 vWF含量、PLT數量和凝血因子時間變化,可以作為DIC早期預測、診斷的重要指標,而且其動態測定結果還可以作為鑑測DIC病情髮展情況、評價療效、判斷疾病嚴重程度和估計預後的重要實驗參數.
목적 탐토vWF함량、PLT수량화응혈인자시간변화재DIC조기진단중적림상개치.방법 혈청vWF측정채용면역비탁법,사용일본산OLYMPUSAU-400전자동생화분석의측정;PT、APTT、TT、Fig측정채용응고법,사용일본산sysmex CA-530응혈분석의측정;PLT계수용EDTA-K2항응정맥혈,사용일본산sysmex K-1000전자동혈세포계수의측정.결과 DIC병례조혈청vWF화Fig함량、PLT수량급PT、APTT、TT시간현저고우정상대조조,차이구유현저성의의(P＜0.01),병수착DIC적발전이축보승고.결론 vWF함량、PLT수량화응혈인자시간변화,가이작위DIC조기예측、진단적중요지표,이차기동태측정결과환가이작위감측DIC병정발전정황、평개료효、판단질병엄중정도화고계예후적중요실험삼수.
Objective Discusses the vWF content, the PLT quantity and the hemoglutination factor time change in the DIC early diagnosis clinical value. Methods The blood serum vWF determination uses the immunity turbidimetric method, uses Japan to produce the OLYMPUSAU-400 completely automatic biochemistry analyzer determination;PT, APIT, TT, the Fig determination uses the coagulation law, uses Japan to produce sysmex the CA-530 hemoglutination analyzer determination;The PLT counting prevents clotting the venous blood with EDTA-K2 , uses Japan to produce sysmex the K-1000 completely automatic blood corpuscle calculating instrument determination. Results DIC case group blood serum vWF and the Fig content, the PLT quantity and PT, APIT, the TT time obviously is higher than the normal control group, the difference had the significance significance(P ＜ 0. 01) , And elevates gradually along with the DIC development. Conclusion The vWF content,the PLT quantity and the hemoglutination factor time variation, may take the DIC early prediction,is important to diagnosis, moreover its dynamic determination result may also take monitors the DIC condition state of play, the appraisal curative effect, the judgment disease order of severity and the estimate prognosis important experiment parameter.
