CAJ | 학술논문

目的探讨急性心肌梗死(AMI)患者血浆脂联素(APN)和超敏C-反应蛋白(h8-CRP)的变化及其临床意义.方法选择AMI患者50例,入院后均行超声心动图检查评价室壁运动和心功能,并设对照组(30例)进行比较.采用ILISA法测定APN,免疫散射比浊法检测hs-CRP水平.结果 AMI患者APN水平显著低于正常心功能对照组(P＜0.01),hs-CRP水平显著高于正常心功能对照组(P＜0.01).AMI患者APN、hs-CRP水平与左心室射血分数(LVEF)呈负相关(r=-0.549,P＜0.01).结论血浆APN、hs-CRP水平与预后显著相关,对AMI的辅助诊断、疗效观察及预后判断具有重要价值.
목적 탐토급성심기경사(AMI)환자혈장지련소(APN)화초민C-반응단백(h8-CRP)적변화급기림상의의.방법 선택AMI환자50례,입원후균행초성심동도검사평개실벽운동화심공능,병설대조조(30례)진행비교.채용ILISA법측정APN,면역산사비탁법검측hs-CRP수평.결과 AMI환자APN수평현저저우정상심공능대조조(P＜0.01),hs-CRP수평현저고우정상심공능대조조(P＜0.01).AMI환자APN、hs-CRP수평여좌심실사혈분수(LVEF)정부상관(r=-0.549,P＜0.01).결론 혈장APN、hs-CRP수평여예후현저상관,대AMI적보조진단、료효관찰급예후판단구유중요개치.
Objective To explore the variation and significance of plasma adiponectin(APN) and high sensitivety C-reactive protein( hs-CRP) in patients with acute myocardial infarction(AMI). Methods The cases were divided into two groups:AMI group (including 50 AMI patients)and control group (including 30 normal individuals). Plasma concentration of APN was measured by ILISA and hs-CRP was measured by immue nephelonretry. Results The concentration of APN in patients with AMI were significantly lower than those in the control group ( P ＜ 0.01 ), hs-CRP were significantly higher than those in the control group ( P ＜ 0.01 ). The concentration of APN and hs-CRP in AMI patients had a parallel rationship with LVEDD (r = 0.549, P ＜ 0,01 ). Conclusion Plasma APN and hsCRP levels are of great value to the diagnosis, treatment and prognosis of AMI.