CAJ | 학술논문

卵黄蛋白原（VTG）广泛存在于卵生脊椎动物和无脊椎动物的卵母细胞中,为卵母细胞的生长和胚胎的发育提供营养。VTG一般在卵巢、肝胰脏和（或）脂肪等组织中合成。VTGcDNA具有较强的保守性,为7 kB左右。VTG具有单体、二聚体等多种形式,其中二聚体有同源二聚体和异源二聚体两种形式。脊椎动物体内,热休克蛋白90（HSP90）通过和雌激素受体结合间接诱导VTG的合成,近年来的研究报道表明HSP90同样对无脊椎动物体内VTG合成也具有诱导作用,但其作用机制有待进一步研究。
란황단백원（VTG）엄범존재우란생척추동물화무척추동물적란모세포중,위란모세포적생장화배태적발육제공영양。VTG일반재란소、간이장화（혹）지방등조직중합성。VTGcDNA구유교강적보수성,위7 kB좌우。VTG구유단체、이취체등다충형식,기중이취체유동원이취체화이원이취체량충형식。척추동물체내,열휴극단백90（HSP90）통과화자격소수체결합간접유도VTG적합성,근년래적연구보도표명HSP90동양대무척추동물체내VTG합성야구유유도작용,단기작용궤제유대진일보연구。
Vitellogenin,the nutrition for the development of the oocyte and the embryo,widely exists in oviparous animals.It is synthesized in ovary,hepatopancreas and/or fatty tissue.Vitellogenin cDNA is about 7kb in length.Vitellogenin protein is monomer,homodimer or heterodimer.In vertebrate,heat shock protein 90 can induce the vitellogenin synthesis,combining with estrogen receptor.Furthermore,recent reports showed that heat shock protein 90 also could induce the vitellogenin synthesis in invertebrate.However the control mechanism still remains unknown in invertebrate.