CAJ | 학술논문

从纳米粒子、水凝胶、纤维材料和环糊精高分子等方面介绍了近年来以环糊精为基础研制的新材料的研究进展。目前以环糊精为基础的纳米粒子材料有核壳结构的纳米粒子、环糊精的化学接枝与共聚、环糊精与无机非金属材料的复合和含环糊精的囊泡材料;以环糊精为基础的凝胶材料有水凝胶和有机凝胶两种材料;此外还有以环糊精为基础的纤维材料、环糊精高分子和其他材料。近几年的研究报道表明,以环糊精为基础的纳米粒子材料作为药物载体和生物材料,具有稳定性好、表面积大的优点;以环糊精为基础的凝胶材料在生物医学领域应用广泛,尤其在药物缓释系统和组织工程支架方面具有特殊优势;以环糊精为基础的纤维材料已经广泛地应用于工业和生活的各个方面。此外,环糊精在吸附材料、分离材料和阻燃材料上也具有很大的应用前景。
종납미입자、수응효、섬유재료화배호정고분자등방면개소료근년래이배호정위기출연제적신재료적연구진전。목전이배호정위기출적납미입자재료유핵각결구적납미입자、배호정적화학접지여공취、배호정여무궤비금속재료적복합화함배호정적낭포재료;이배호정위기출적응효재료유수응효화유궤응효량충재료;차외환유이배호정위기출적섬유재료、배호정고분자화기타재료。근궤년적연구보도표명,이배호정위기출적납미입자재료작위약물재체화생물재료,구유은정성호、표면적대적우점;이배호정위기출적응효재료재생물의학영역응용엄범,우기재약물완석계통화조직공정지가방면구유특수우세;이배호정위기출적섬유재료이경엄범지응용우공업화생활적각개방면。차외,배호정재흡부재료、분리재료화조연재료상야구유흔대적응용전경。
A brief introduction of novel materials based on cyclodextrins is summarized from the following aspects： nanoparticles,gels,fibers,and cyclodextrin polymers.Applications in chemical and pharmaceutical industries and outlook of cyclodextrins are discussed.Nanoparticle materials based on cylodextrins consist of core-shell,copolymerization,complexed inorganic nonmetallic materials and vesicles materials.The gels materials consist of β-cyclodextrin hydrogel and cyclodextrin organogels.Many studies showed that nanoparticle materials based on cylodextrins have the advantages of high surface area and stability as drug carriers and biological materials,and that gels materials based on cyclodextrin have been widely used in biomedical application,especially drugs slow-release system and tissue engineering.Fiber materials based on cyclodextrin widely have been used in the applications of industrial and living fields.In addition,cyclodextrins are one of the most promising materials for adsorbing,separation and flame-resisting materials.