CAJ | 학술논문

目的调查绝经后女性的体成分与年龄、绝经年龄、绝经年限和腰椎、髋部BMD之间的关系.方法用双能X线骨密度仪测量919例绝经后女性的体成分、正位腰椎和髋部BMD.结果下身脂肪量、全身脂肪量和全身瘦组织量与年龄、绝经年龄和绝经年限都相关(P＜0.05～0.01),但只有绝经年限进入体成分的多元逐步回归方程,采用复合或三次回归模型拟合优度最佳.体成分随绝经年限的延长有下降趋势.绝经10年以上女性的下身脂肪量和全身瘦组织量显著减少,分别较绝经年限5年以内女性下降8.6%和3.1%.所有部位的体成分与所测区域的BMD 均呈正相关(P＜0.05～0.01),控制体重变量后,仅有全身脂肪量与腰椎BMD 呈正相关(P＜0.05),而全身瘦组织量与髋部BMD 呈正相关(P＜0.05).多元逐步回归分析发现体成分是影响腰椎和髋部BMD的一个重要因素,但对腰椎BMD影响最大的是全身脂肪量,而对髋部BMD影响最大的是全身瘦组织量.BMD 越低者,全身脂肪量和全身瘦组织量也越低,组间比较有显著性差异.结论绝经后女性的体成分与年龄、绝经年龄、绝经年限和腰椎、髋部BMD相关,其中,绝经年限对体成分的影响最大,体成分组分对BMD的影响存在部位差异.
목적 조사절경후녀성적체성분여년령、절경년령、절경년한화요추、관부BMD지간적관계.방법 용쌍능X선골밀도의측량919례절경후녀성적체성분、정위요추화관부BMD.결과 하신지방량、전신지방량화전신수조직량여년령、절경년령화절경년한도상관(P＜0.05～0.01),단지유절경년한진입체성분적다원축보회귀방정,채용복합혹삼차회귀모형의합우도최가.체성분수절경년한적연장유하강추세.절경10년이상녀성적하신지방량화전신수조직량현저감소,분별교절경년한5년이내녀성하강8.6%화3.1%.소유부위적체성분여소측구역적BMD 균정정상관(P＜0.05～0.01),공제체중변량후,부유전신지방량여요추BMD 정정상관(P＜0.05),이전신수조직량여관부BMD 정정상관(P＜0.05).다원축보회귀분석발현체성분시영향요추화관부BMD적일개중요인소,단대요추BMD영향최대적시전신지방량,이대관부BMD영향최대적시전신수조직량.BMD 월저자,전신지방량화전신수조직량야월저,조간비교유현저성차이.결론 절경후녀성적체성분여년령、절경년령、절경년한화요추、관부BMD상관,기중,절경년한대체성분적영향최대,체성분조분대BMD적영향존재부위차이.
Objective To investigate the relationships of body composition with age, menopausal age, years since menopause (YSM) and areal bone mineral density (BMD) at posteroanterior spine and hip in postmenopausal women.Methods Body composition and BMD at posteroanterior spine and hip were measured by dual-energy X-ray absorptiometry (DXA) in 919 postmenopausal women.Results Lower body fat mass (LF), whole fat mass (WF) and whole lean mass (WL) were all correlated with age, menopausal age and YSM (P＜0.05～0.01), while only YSM entered multiple stepwise regression equation of body composition and the goodness of fit in complex or cubic regression model was best.Body composition had a downward trend with YSM.LF and WL reduced significantly in the women with YSM over 10 years, which were lower 8.6% and 3.1% compared to those of the women with YSM within 5 years respectively.All regional body composition was positively correlated with all regional BMD (P＜0.05～0.01).After controlling body weight, only WF was related to BMD at posteroanterior spine (P＜0.05), while WL was related to BMD at hip (P＜0.05).Multiple stepwise regression analysis revealed that body composition was an important variable that affected the BMDs at lumbar spine and hip and WF was the main determinant of BMD at lumbar spine while WL was the main determinant of BMD of hip.Lower BMD, lower WF and WL.The difference of WF and WL was significant among different BMD groups.Conclusions Body composition is related with age, menopausal age, YSM and BMD at posteroanterior spine and hip in postmenopausal women; YSM is the most important influencing factor to body composition; there is regional difference in the effects of body composition components on BMD.