CAJ | 학술논문

成都大熊猫繁育研究基地对圈养的7只8～21岁的大熊猫血清犬瘟热病毒(CDV)中和抗体滴度进行了测定.结果显示,尽管这些大熊猫自2003年起每年接受2次CDV弱毒疫苗接种,该弱毒疫苗是由未知家犬犬瘟热病毒株制作的,大熊猫血清犬瘟热病毒中和抗体滴度却在2×到256×的较大范围内(平价值=16)波动.通常单次的麻疹病毒弱毒疫苗注射足以导致宿主产生相应的稳定的免疫反应,在大熊猫上抗犬瘟热中和抗体变化幅度较大提示在宿主与疫苗的关系中存在某种程度的不足.
성도대웅묘번육연구기지대권양적7지8～21세적대웅묘혈청견온열병독(CDV)중화항체적도진행료측정.결과현시,진관저사대웅묘자2003년기매년접수2차CDV약독역묘접충,해약독역묘시유미지가견견온열병독주제작적,대웅묘혈청견온열병독중화항체적도각재2×도256×적교대범위내(평개치=16)파동.통상단차적마진병독약독역묘주사족이도치숙주산생상응적은정적면역반응,재대웅묘상항견온열중화항체변화폭도교대제시재숙주여역묘적관계중존재모충정도적불족.
Canine distemper virus (CDV) neutralizing antibody (NT) titer was examined against the sera from 7 giant pandas aged between 8 to 21 years housed at Chengdu Research Base of Giant Panda Breeding,China.Anti-CDV NT titer against the Onderstepoort strain showed a wide range from × 2 to×256 (median=16),even though the ani-mals had been receiving an attenuated live vaccine made from an anonymous domestic CDV strain twice a year since 2003.A single administration of attenuated morbillivirus antigen often be enough to give corresponding host a steady immunogenicity.Anti-CDV-NT variation in the giant panda suggests some deficiency in the relationship between the vaccine and the host.