放射免疫学杂志
放射免疫學雜誌
방사면역학잡지
JOURNAL OF RADIOMMUNOLOGY
2007年
4期
352-355
,共4页
抗甲状腺球蛋白抗体%抗甲状腺过氧化物酶抗体%国家标准品
抗甲狀腺毬蛋白抗體%抗甲狀腺過氧化物酶抗體%國傢標準品
항갑상선구단백항체%항갑상선과양화물매항체%국가표준품
目的:为规范国产Anti-TgAb 和Anti-TpoAb定量测定试剂盒,本实验室研制并建立了Anti-TgAb 和Anti-TpoAb免疫测定用国家标准品.方法和结果:选择经临床检测Anti-TgAb、Anti-TpoAb高值血清,经离心、过滤等处理后,分装、冻干制成标准品候选品.以WHO Anti-TgAb 1st IRP (65/093)为对照品,经协作标定,候选品中Anti-TgAb免疫活性均值为3691IU/支,以WHO Anti-TpoAb RS (66/387)为对照品,经协作标定,候选品中Anti-TpoAb免疫活性均值为434IU/支.结论:本标准品中Anti-TgAb免疫活性定义为4000IU/支,Anti-TpoAb免疫活性定义为430IU/支.本标准品的建立,为国产Anti-TgAb 和Anti-TpoAb试剂盒提供了定量依据,本文还对目前国内常用的几种进口Anti-TgAb 和Anti-TpoAb定量免疫分析试剂盒进行了比较分析,供临床和检验医生参考.
目的:為規範國產Anti-TgAb 和Anti-TpoAb定量測定試劑盒,本實驗室研製併建立瞭Anti-TgAb 和Anti-TpoAb免疫測定用國傢標準品.方法和結果:選擇經臨床檢測Anti-TgAb、Anti-TpoAb高值血清,經離心、過濾等處理後,分裝、凍榦製成標準品候選品.以WHO Anti-TgAb 1st IRP (65/093)為對照品,經協作標定,候選品中Anti-TgAb免疫活性均值為3691IU/支,以WHO Anti-TpoAb RS (66/387)為對照品,經協作標定,候選品中Anti-TpoAb免疫活性均值為434IU/支.結論:本標準品中Anti-TgAb免疫活性定義為4000IU/支,Anti-TpoAb免疫活性定義為430IU/支.本標準品的建立,為國產Anti-TgAb 和Anti-TpoAb試劑盒提供瞭定量依據,本文還對目前國內常用的幾種進口Anti-TgAb 和Anti-TpoAb定量免疫分析試劑盒進行瞭比較分析,供臨床和檢驗醫生參攷.
목적:위규범국산Anti-TgAb 화Anti-TpoAb정량측정시제합,본실험실연제병건립료Anti-TgAb 화Anti-TpoAb면역측정용국가표준품.방법화결과:선택경림상검측Anti-TgAb、Anti-TpoAb고치혈청,경리심、과려등처리후,분장、동간제성표준품후선품.이WHO Anti-TgAb 1st IRP (65/093)위대조품,경협작표정,후선품중Anti-TgAb면역활성균치위3691IU/지,이WHO Anti-TpoAb RS (66/387)위대조품,경협작표정,후선품중Anti-TpoAb면역활성균치위434IU/지.결론:본표준품중Anti-TgAb면역활성정의위4000IU/지,Anti-TpoAb면역활성정의위430IU/지.본표준품적건립,위국산Anti-TgAb 화Anti-TpoAb시제합제공료정량의거,본문환대목전국내상용적궤충진구Anti-TgAb 화Anti-TpoAb정량면역분석시제합진행료비교분석,공림상화검험의생삼고.
