CAJ | 학술논문

目的：探讨X刀在脑转移瘤治疗中的临床价值。方法：回顾分析X刀治疗的30例脑转移瘤患者(41个病灶)，脑转移瘤直径(2.07±1.7)cm，平均剂量22 Gy，肿瘤中心剂量(28±8)Gy，边缘剂量(16±4)Gy。比较分析手术加全脑放射治疗26例，直径(3.07±0.7)cm，平均放疗剂量46 Gy。结果：X刀治疗组1年生存率53％，手术加全脑放疗组43％，1年后局部肿瘤控制率分别为83％和75％，1年后因神经系统疾患死亡率分别为39％和41％。结论：X刀是一种安全、有效和微侵袭的治疗方法，适用于中小体积脑转移瘤的治疗。
목적：탐토X도재뇌전이류치료중적림상개치。방법：회고분석X도치료적30례뇌전이류환자(41개병조)，뇌전이류직경(2.07±1.7)cm，평균제량22 Gy，종류중심제량(28±8)Gy，변연제량(16±4)Gy。비교분석수술가전뇌방사치료26례，직경(3.07±0.7)cm，평균방료제량46 Gy。결과：X도치료조1년생존솔53％，수술가전뇌방료조43％，1년후국부종류공제솔분별위83％화75％，1년후인신경계통질환사망솔분별위39％화41％。결론：X도시일충안전、유효화미침습적치료방법，괄용우중소체적뇌전이류적치료。
Objectlve To explore the clinical value of X-ray knife in the treatment of brain metastases.Methods 30 patients with brain metastases of 41 lesions treated by X-ray knife were analysed retrospectively,the diameters of the brain metastases were(2.07 ± 1 .7)cm,the mean dose given by X- ray knife was 22 Gy,the centraldoses were (28 ± 8 ) Gy, and the peripheral doses were ( 16 ± 4) Gy. 26 patients with brain metastasesreceived surgical resection combined with whole brain radiotherapy were analysed comparatively, the diametersof the lesions in the latter group were(3.07 ± 0.7)cm, and the mean whole brain radiation dose was 46 Gy. Re-sults The 1-year survival rate of patients in X-ray knife group was 53 %, and 43 % in the surgery group ( P =0.19). The 1-year local tumor control rates were 83 % and 75 % in the two groups, respectively (P = 0.49).The 1-year neurological disease-specific death rates were 39% and 41%, respectively. Conclusions X-rayknife is a safe, effective and minimally invasive treatment method for the small brain metastases.