CAJ | 학술논문

顺式-1-甲氧羰基-2-芳基-6,6-二甲基-5,7-二氧螺环[2,5]-4,8-辛二酮与联苯二胺(Ⅱ0)或4,4′-亚甲基二苯胺 (Ⅱ1)在二氯甲烷中,40℃搅拌反应合成得到化合物Ⅲ0 和Ⅲ1,干燥后进一步在二甲苯中回流即可得到N,N′-取代-双-(反式-β,γ-二取代-γ-丁内酰胺) (Ⅳ0或Ⅳ1), 得率高, 立体选择性好, 方法简便.
순식-1-갑양탄기-2-방기-6,6-이갑기-5,7-이양라배[2,5]-4,8-신이동여련분이알(Ⅱ0)혹4,4′-아갑기이분알 (Ⅱ1)재이록갑완중,40℃교반반응합성득도화합물Ⅲ0 화Ⅲ1,간조후진일보재이갑분중회류즉가득도N,N′-취대-쌍-(반식-β,γ-이취대-γ-정내선알) (Ⅳ0혹Ⅳ1), 득솔고, 입체선택성호, 방법간편.
cis-1-Methoxycarbonyl-2-aryl-6,6-dimethyl-5,7-dioxa-spiro[2,5]-4,6-octadiones reacted with benzidine (Ⅱ0) or 4,4′-methylenedianiline (Ⅱ1) at 40℃ to give product Ⅲ0or Ⅲ1 which were further refluxed in xylene to get N,N′-(4,4′-biphenylene) bis (trans-β-methoxycarbonyl-γ-substituted phenyl-γ-butyrolactam) (Ⅳ0) or N,N′-(methylenedi-4,4′-phenylene) bis (trans-β-methoxycarbonyl-γ-substituted phenyl-γ-butyrolactam) (Ⅳ1) in good yield with high stereoselectivity.