国际内分泌代谢杂志
國際內分泌代謝雜誌
국제내분비대사잡지
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2010年
3期
168-170
,共3页
维生素D%维生素D受体%肥胖
維生素D%維生素D受體%肥胖
유생소D%유생소D수체%비반
Vitamin D%Vitamin D receptor%Obesity
大量研究表明维生素D及维牛素D受体(VDR)与肥胖密切相关.血清25(OH)D及1,25(OH),D的浓度都与体重指数(BMI)呈负相关.潜在的原因可能是由于肥胖者活动少及着装习惯导致的日光照射少以及大量的维生素D储存于脂肪组织中所致.研究发现,补充维生素D有利于减轻体重.因此,肥胖者比非肥胖者更需要补充维生素D.只有增加安全、合适的日照时间,食用强化维生素D的食品或者补充高剂量的维牛素D才能保证体内充足的维生素D水平.
大量研究錶明維生素D及維牛素D受體(VDR)與肥胖密切相關.血清25(OH)D及1,25(OH),D的濃度都與體重指數(BMI)呈負相關.潛在的原因可能是由于肥胖者活動少及著裝習慣導緻的日光照射少以及大量的維生素D儲存于脂肪組織中所緻.研究髮現,補充維生素D有利于減輕體重.因此,肥胖者比非肥胖者更需要補充維生素D.隻有增加安全、閤適的日照時間,食用彊化維生素D的食品或者補充高劑量的維牛素D纔能保證體內充足的維生素D水平.
대량연구표명유생소D급유우소D수체(VDR)여비반밀절상관.혈청25(OH)D급1,25(OH),D적농도도여체중지수(BMI)정부상관.잠재적원인가능시유우비반자활동소급착장습관도치적일광조사소이급대량적유생소D저존우지방조직중소치.연구발현,보충유생소D유리우감경체중.인차,비반자비비비반자경수요보충유생소D.지유증가안전、합괄적일조시간,식용강화유생소D적식품혹자보충고제량적유우소D재능보증체내충족적유생소D수평.
Accumulating evidence suggests that vitamin D and vitamin D receptor( VDR) are related to obesity. Serum 25(OH)D and 1,25(OH)2D levels are inversely associated with body mass index(BMI). Underlying causes that have been suggested are less sun exposure in obese subjects due to limited mobility or clothing habits and a higher storage of vitamin D in adipose tissue. Restoration of vitamin D helps to lose weight. Thus, more vitamin D are needed in obese subjects than non-obese subjects. Correction of low 25 (OH) D concentrations can happen only if some or all of the following are implemented: the encouragement of safe, moderate exposure of skin to ultraviolet light, appropriate increase in food fortification with vitamin D,and the provision of higher doses of vitamin D in supplements for adults.
