CAJ | 학술논문

目的探讨中药膳食联合生活方式(糖尿病知识教育、运动、饮食、减肥等)干预对糖调节受损(IGR)患者的作用效果.方法将社区200例IGR患者随机分为三组,空白组(n=67),予一般糖尿病教育,对照组(n=67)予生活方式指导,干预组(n=66)予生活方式指导联合中药膳食干预.18个月后比较三组IGR患者转归情况及空腹血糖(FBG)、餐后2 h血糖(2 h PG)及体重指数(BMI)的变化.结果空白组、对照组、干预组三组IGR患者逆转为正常血糖分别为5.97%,29.85%,59.09%;稳定在IGR阶段者分别为79.10%,64.18%,37.88%;发展为糖尿病者分别为14.93%,5.97%,3.03%;对照组、干预组与空白组比较,干预组与对照组比较差异均有统计学意义(P＜O.01).对照组、干预组患者的FBG、2 h PG及BMI与空白组比较差异均有统计学意义(P＜0.01).结论对IGR患者,在生活方式指导的同时进行中药膳食干预,可进一步降低FBG及2 h PG,并改善IGR患者的临床转归.
목적 탐토중약선식연합생활방식(당뇨병지식교육、운동、음식、감비등)간예대당조절수손(IGR)환자적작용효과.방법 장사구200례IGR환자수궤분위삼조,공백조(n=67),여일반당뇨병교육,대조조(n=67)여생활방식지도,간예조(n=66)여생활방식지도연합중약선식간예.18개월후비교삼조IGR환자전귀정황급공복혈당(FBG)、찬후2 h혈당(2 h PG)급체중지수(BMI)적변화.결과 공백조、대조조、간예조삼조IGR환자역전위정상혈당분별위5.97%,29.85%,59.09%;은정재IGR계단자분별위79.10%,64.18%,37.88%;발전위당뇨병자분별위14.93%,5.97%,3.03%;대조조、간예조여공백조비교,간예조여대조조비교차이균유통계학의의(P＜O.01).대조조、간예조환자적FBG、2 h PG급BMI여공백조비교차이균유통계학의의(P＜0.01).결론 대IGR환자,재생활방식지도적동시진행중약선식간예,가진일보강저FBG급2 h PG,병개선IGR환자적림상전귀.
Objective To investigate effects of combining Traditional Chinese Medicine (TCM) diet with lifestyle interference including disease related knowledge education, movement guidance, diet management and lose weight guidance on the patients with impaired glucose regulation (IGR). Methods A total of 200cases of community IGR patients were divided into three groups randomly:67 cases in blank group , 67 cases in comparison group and 66 cases in study group. The comparison group was performed lifestyle guidance while the study group was conducted TCM diet combination with lifestyle interference. Clinical outcomes containing FBG,2h PG and BMI were compared at 18 month later among three groups. Results After 18 months, in the three groups(blank groups, the comparison group and the study group)5.97%, 29.85% and 59.09% patients reverted to normal glucose tolerance, 79.10%, 64. 18% and 37.88% patients remained IGR and 14.93%,5.97% and 3.03% patients progressed into the diabetes mellitus. FBG, 2h PG and BMI were significantly different when the comparison group compared with the study group and the blank group compared with the study group or the comparison group. Conclusions Combining TCM diet with lifestyle interference can lower the FBG and 2h PG and improve the clinical outcome for patients with IGR.