中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2009年
2期
108-110
,共3页
杭荣华%刘新民%程万良%吴义高
杭榮華%劉新民%程萬良%吳義高
항영화%류신민%정만량%오의고
精神分裂症%抑郁症%执行功能%认知功能
精神分裂癥%抑鬱癥%執行功能%認知功能
정신분렬증%억욱증%집행공능%인지공능
Schizophrenia%Depression%Executive functions%Cognitive functions
目的 研究精神分裂症和抑郁症患者的认知功能.方法 采用韦氏成人智力量表、韦氏记忆量表和威斯康星卡片分类测验评估34例精神分裂症、35例抑郁症和37例正常对照的认知功能.结果 1.精神分裂症和抑郁症患者的智商、记忆和威斯康星卡片分类测验成绩均差于对照组.2.抑郁症患者与精神分裂症患者的完成分类数[(4.09±1.27)个,(1.53±1.00)个]、错误应答数[(39.17±17.89)个,(50.41±26.44)个]、持续错误百分数[(20.86±11.29)%,(26.56±13.05)%]、随机错误百分数[(14.40±7.81)%,(24.67±14.50)%]和概念化水平[53.56±17.32)%,(31.30±16.21)%])差异有显著性.3.抑郁症患者和Ⅱ型精神分裂症患者在完成分类数[(4.09±1.27)个,(1.50±0.16)个]、随机错误百分数[(14.40±7.81)%,(27.87±16.39)%]和概念化水平[(53.56±17.32)%,(23.89±14.88)%]方面差异有显著性.结论 精神分裂症和抑郁症患者认知功能损害广泛而全面,精神分裂症执行功能损害比抑郁症更严重,阴性症状可能与精神分裂症的执行功能损害有关.
目的 研究精神分裂癥和抑鬱癥患者的認知功能.方法 採用韋氏成人智力量錶、韋氏記憶量錶和威斯康星卡片分類測驗評估34例精神分裂癥、35例抑鬱癥和37例正常對照的認知功能.結果 1.精神分裂癥和抑鬱癥患者的智商、記憶和威斯康星卡片分類測驗成績均差于對照組.2.抑鬱癥患者與精神分裂癥患者的完成分類數[(4.09±1.27)箇,(1.53±1.00)箇]、錯誤應答數[(39.17±17.89)箇,(50.41±26.44)箇]、持續錯誤百分數[(20.86±11.29)%,(26.56±13.05)%]、隨機錯誤百分數[(14.40±7.81)%,(24.67±14.50)%]和概唸化水平[53.56±17.32)%,(31.30±16.21)%])差異有顯著性.3.抑鬱癥患者和Ⅱ型精神分裂癥患者在完成分類數[(4.09±1.27)箇,(1.50±0.16)箇]、隨機錯誤百分數[(14.40±7.81)%,(27.87±16.39)%]和概唸化水平[(53.56±17.32)%,(23.89±14.88)%]方麵差異有顯著性.結論 精神分裂癥和抑鬱癥患者認知功能損害廣汎而全麵,精神分裂癥執行功能損害比抑鬱癥更嚴重,陰性癥狀可能與精神分裂癥的執行功能損害有關.
목적 연구정신분렬증화억욱증환자적인지공능.방법 채용위씨성인지역량표、위씨기억량표화위사강성잡편분류측험평고34례정신분렬증、35례억욱증화37례정상대조적인지공능.결과 1.정신분렬증화억욱증환자적지상、기억화위사강성잡편분류측험성적균차우대조조.2.억욱증환자여정신분렬증환자적완성분류수[(4.09±1.27)개,(1.53±1.00)개]、착오응답수[(39.17±17.89)개,(50.41±26.44)개]、지속착오백분수[(20.86±11.29)%,(26.56±13.05)%]、수궤착오백분수[(14.40±7.81)%,(24.67±14.50)%]화개념화수평[53.56±17.32)%,(31.30±16.21)%])차이유현저성.3.억욱증환자화Ⅱ형정신분렬증환자재완성분류수[(4.09±1.27)개,(1.50±0.16)개]、수궤착오백분수[(14.40±7.81)%,(27.87±16.39)%]화개념화수평[(53.56±17.32)%,(23.89±14.88)%]방면차이유현저성.결론 정신분렬증화억욱증환자인지공능손해엄범이전면,정신분렬증집행공능손해비억욱증경엄중,음성증상가능여정신분렬증적집행공능손해유관.
Objective To explore the cognitive function of schizophrenic patients and depressive patients. Methods Wechsler Adult Intelligence Scale (WAIS-RC), Wechsler Memory Scale (WMS) and Wisconsin Card Sorting Test (WCST) were adopted to assess the cognitive function of schizophrenic patients(n =34),depressive patients(n =35) and normal cotrol(n =37). Results The intelligence, memory and WCST performance of schizophrenic and depressive patients were lower than that of the control group. All the WCST performances of schizophrenic group were worse than that of the depressive group Cc[(4.09±1.27) vs (1.53±1.00)],Re[(39.17±17.89) vs (50.41±26.44)],Rpe%[(20.86±11.29)% vs (26.56±13.05)%],nRpe%[(14.40±7.81)% vs (27.87±16.39)%],Rf%[(53.56±17.32)% vs (23.89±14.88)%].The performance of the type Ⅱschizophrenic group were worse than that of the depressive group in correct classification [(4.09±1.27) vs (1.53±1.00)], random errors percentage [(14.40±7.81)% vs (27.87±16.39)%] and conceptual level [(53.56±17.32)% vs (23.89±14.88)%]. Conclusion There was comprehensive impairment in the cognitive function of the schizophrenic and the depressed patients. The impairment of the executive function of the schizophrenic group was worse than that of the depressive group. Negative symptoms of schizophrenic patients are probably related to the impairment of executive function.
