中国科学B辑(英文版)
中國科學B輯(英文版)
중국과학B집(영문판)
SCIENCE IN CHINA(SCIENTIA SINICA)
2002年
4期
337-348
,共12页
林长学%李艳梅%成昌梅%韩波%万荣%冯亚兵%赵玉芬
林長學%李豔梅%成昌梅%韓波%萬榮%馮亞兵%趙玉芬
림장학%리염매%성창매%한파%만영%풍아병%조옥분
penta-coordinate phosphorus compounds%biochemistry%nucleotide%amino acid%origin of life
The relationship between penta-coordinate phosphorus compounds and biochemistry is briefly reviewed. Some interesting phenomena such as peptide formation, ester formation, ester exchange on phosphorus and N to O migration occur at room temperature when the amino group of amino acid is associated with phosphoryl group. Serine or threonine in conjugate of nucleoside-amino acid could recognize different nucleobases. N-phosphoryl Histine and Ser-His dipeptide could cleavage nucleic acid, protein and ester in neutral medium. It is found that the above phenomena all undergo penta-coordinate intermediate of phosphorus atom, which is proposed as the key factor to determine their activities.
