CAJ | 학술논문

2008年12月,西南大学家蚕基因组研究团队宣布了世界上第1张家蚕基因组精细图谱的诞生.家蚕基因组精细图和2003年发布的家蚕基因组框架图相比,具有基因覆盖度高、基因组组装更加完整、基因鉴定更加准确等特点.2009年,该研究团队在家蚕基因组精细图的基础上,选取具有代表性的29个家蚕突变品系和11个不同地理来源的中国野桑蚕品系进行了全基因组重测序与序列比较分析,共获得了29个家蚕突变品系和11个中国野桑蚕地理品系的全基因组序列,绘制完成了世界上第1张基因组水平上的蚕类单碱基遗传变异图谱,同时还发现了驯化对家蚕生物学性状影响的基因组印记,从全基因组水平上揭示了家蚕的起源进化.2009年8月,<Science>杂志发表了西南大学的研究论文"40个蚕类基因组的重测序揭示了家蚕的驯化事件及驯化相关基因",标志着家蚕基因组计划进入一个新的历史阶段.
2008년12월,서남대학가잠기인조연구단대선포료세계상제1장가잠기인조정세도보적탄생.가잠기인조정세도화2003년발포적가잠기인조광가도상비,구유기인복개도고、기인조조장경가완정、기인감정경가준학등특점.2009년,해연구단대재가잠기인조정세도적기출상,선취구유대표성적29개가잠돌변품계화11개불동지리래원적중국야상잠품계진행료전기인조중측서여서렬비교분석,공획득료29개가잠돌변품계화11개중국야상잠지리품계적전기인조서렬,회제완성료세계상제1장기인조수평상적잠류단감기유전변이도보,동시환발현료순화대가잠생물학성상영향적기인조인기,종전기인조수평상게시료가잠적기원진화.2009년8월,<Science>잡지발표료서남대학적연구논문"40개잠류기인조적중측서게시료가잠적순화사건급순화상관기인",표지착가잠기인조계화진입일개신적역사계단.
In December 2008, the silkworm genome research team of Southwest University of China announced that the first fine genome map of domesticated silkworm (Bombyx mori) was completed in the world. Compared to the draft genome sequences released in 2003, the fine map is characterized by its deeper gene coverage, more complete genome assembly, and more accurate genetic identification etc. In 2009, based on the fine genome map of domesticated silkworm, this research team selected 29 representative domesticated silkworm strains and 11 wild silkworm strains from various geographic locations in China for re-sequencing and sequence comparative analyses. As a result, the whole genome sequences of 29 mutant strains of domesticated silkworm and 11 geographic strains of Bombyx mandarina M. were obtained. And the first genome-wide single-base genetic variation map of silkworm was generated. Meanwhile, genomic imprints relevant to the influence of domestication on silkworm biological characters were discovered, revealing important origination and evolutionary events of silkworm on genome-wide level. In August 2009, the report titled "Complete Resequencing of 40 Genomes Reveals Domestication Events and Genes in Silkworm (Bombyx)" of Southwest University was published in Science, signaling that the Silkworm Genome Project has entered a new historical phase.