CAJ | 학술논문

目的研究慢性乙型肝炎、乙型肝炎肝硬化患者幽门螺旋杆菌感染情况.方法选取本院2008年9月至2010年8月门诊和住院胃镜检查患者1109例,其中慢性乙型肝炎患者552例、乙型肝炎肝硬化患者344例,普通患者213例,对三组患者幽门螺旋杆菌(Hp)感染情况进行比较分析.结果普通患者、慢性乙型肝炎、乙型肝炎肝硬化患者的Hp感染率分别为23.5％( 50/213)、24.8％ (137/552)、28.5％(98/344),三组比较差异无统计学意义(x2=2.17,P＞0.05).肝硬化门静脉高压征轻、中、重度患者Hp感染率分别为34.2％ (53/155)、23.7％(23/97)和23.9％ (22/92),三者差异无统计学意义(x2 =4.46,P＞0.05).结论 Hp感染在慢性乙型肝炎和乙型肝炎肝硬化患者中的感染率与普通患者类似,Hp感染对肝硬化门静脉高压征并无影响.
목적 연구만성을형간염、을형간염간경화환자유문라선간균감염정황.방법 선취본원2008년9월지2010년8월문진화주원위경검사환자1109례,기중만성을형간염환자552례、을형간염간경화환자344례,보통환자213례,대삼조환자유문라선간균(Hp)감염정황진행비교분석.결과 보통환자、만성을형간염、을형간염간경화환자적Hp감염솔분별위23.5％( 50/213)、24.8％ (137/552)、28.5％(98/344),삼조비교차이무통계학의의(x2=2.17,P＞0.05).간경화문정맥고압정경、중、중도환자Hp감염솔분별위34.2％ (53/155)、23.7％(23/97)화23.9％ (22/92),삼자차이무통계학의의(x2 =4.46,P＞0.05).결론 Hp감염재만성을형간염화을형간염간경화환자중적감염솔여보통환자유사,Hp감염대간경화문정맥고압정병무영향.
Objective To study Helicobacter pylori (Hp) infection situation in chronic hepatitis B and liver cirrhosis patients.Methods 1109 outpatients or inpatients who were examined by gastroscopy in our hospital between September 2008 and August 2010 were selected.All the patients were divided into 3 groups:chronic hepatitis B patients (552 cases),liver cirrhosis patients (344 cases) and general patients (213 cases).Hp infection rates in 3 groups were analyzed and compared.Results There were 50,137 and 98 cases of Hp positive in general patients,chronic hepatitis B and liver cirrhosis patients respectively.The rate of Hp infection in three groups were 23.5％,24.8％ and 28.5％ respectively.There were no statistical differences among the three groups( x2 =2.17,P ＞ 0.05).The rate of Hp infection in mild,moderate and severe hepatic cirrhotic portal hypertension were 34.2％(53/155),23.7％(23/97) and 23.9％(22/92) respectively,and there were no statistical differences( x2 =4.46,P ＞ 0.05).Conclusions Hp infection rate in chronic hepatitis B patients and liver cirrhosis patients were similar to general patients.Hp infection has no effect on hepatic cirrhotic portal hypertension.