中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2008年
5期
521-522
,共2页
陈小琳%李竞%文重远%孙永林%王颖%蔡小俐%周波%李珍瑾
陳小琳%李競%文重遠%孫永林%王穎%蔡小俐%週波%李珍瑾
진소림%리경%문중원%손영림%왕영%채소리%주파%리진근
肥胖症%糖尿病,2型%一级亲属%胰岛素抵抗%C反应蛋白质
肥胖癥%糖尿病,2型%一級親屬%胰島素牴抗%C反應蛋白質
비반증%당뇨병,2형%일급친속%이도소저항%C반응단백질
Obesity%Diabetes mellitus,type 2%First-degree relatives%Insulin resistance%C-reactive protein
观察肥胖和非肥胖葡萄糖耐量正常的2型糖尿病一级亲属胰岛素敏感性、β细胞功能和血清超敏C反应蛋白(hs-CRP)水平,结果显示肥胖2型糖尿病一级亲属存在胰岛素抵抗、β细胞功能受损和hs-CRP水平升高,且胰岛素抵抗、hs-CRP与腰围正相关.
觀察肥胖和非肥胖葡萄糖耐量正常的2型糖尿病一級親屬胰島素敏感性、β細胞功能和血清超敏C反應蛋白(hs-CRP)水平,結果顯示肥胖2型糖尿病一級親屬存在胰島素牴抗、β細胞功能受損和hs-CRP水平升高,且胰島素牴抗、hs-CRP與腰圍正相關.
관찰비반화비비반포도당내량정상적2형당뇨병일급친속이도소민감성、β세포공능화혈청초민C반응단백(hs-CRP)수평,결과현시비반2형당뇨병일급친속존재이도소저항、β세포공능수손화hs-CRP수평승고,차이도소저항、hs-CRP여요위정상관.
Insulin sensitivity,β-cell function and serum high-sensitivity C-reactive protein (hs-CRP)levels were observed in obese and non-obese normoglycemic first-degree relatives of type 2 diabetic patients (FDR). The results showed that there existed insulin resistance,β-cell dysfunction and increased serum hs-CRP level in obese FDR of type 2 diabetic patients. Moreover, insulin resistance and increased CRP level were positively related to waist circumference.
