中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
1期
28-30
,共3页
脂肪因子%网膜素%葡萄糖代谢
脂肪因子%網膜素%葡萄糖代謝
지방인자%망막소%포도당대사
Adipokine%Omentin%Glucose metabolism
目的 研究血浆网膜素与糖代谢的关系.方法 入选者85例,行糖耐量试验分为糖尿病组42例,糖调节受损组17例,糖代谢正常组26例.均空腹经肘静脉抽取静脉血,采用ELISA法测定血浆网膜素水平.结果 糖代谢正常组、糖调节受损组、糖尿病组血浆网膜素水平分别为(53.7±7.7)、(40.7±9.9)、(30.6±5.3)μg/L,差异有统计学意义(P=0.049).且糖尿病组和糖代谢正常组比较差异有统计学意义(P=0.014).糖代谢正常者血浆网膜素水平为(53.7±7.7)μg/L,糖代谢异常者为(33.5±6.0)μg/L,两者比较差异有统计学意义(P=0.023).多因素Logistic回归分析显示血浆网膜素水平下降是糖代谢异常的独立危险因素(P=0.027).结论 网膜素可能在糖代谢异常的发生机制中起到一定作用.
目的 研究血漿網膜素與糖代謝的關繫.方法 入選者85例,行糖耐量試驗分為糖尿病組42例,糖調節受損組17例,糖代謝正常組26例.均空腹經肘靜脈抽取靜脈血,採用ELISA法測定血漿網膜素水平.結果 糖代謝正常組、糖調節受損組、糖尿病組血漿網膜素水平分彆為(53.7±7.7)、(40.7±9.9)、(30.6±5.3)μg/L,差異有統計學意義(P=0.049).且糖尿病組和糖代謝正常組比較差異有統計學意義(P=0.014).糖代謝正常者血漿網膜素水平為(53.7±7.7)μg/L,糖代謝異常者為(33.5±6.0)μg/L,兩者比較差異有統計學意義(P=0.023).多因素Logistic迴歸分析顯示血漿網膜素水平下降是糖代謝異常的獨立危險因素(P=0.027).結論 網膜素可能在糖代謝異常的髮生機製中起到一定作用.
목적 연구혈장망막소여당대사적관계.방법 입선자85례,행당내량시험분위당뇨병조42례,당조절수손조17례,당대사정상조26례.균공복경주정맥추취정맥혈,채용ELISA법측정혈장망막소수평.결과 당대사정상조、당조절수손조、당뇨병조혈장망막소수평분별위(53.7±7.7)、(40.7±9.9)、(30.6±5.3)μg/L,차이유통계학의의(P=0.049).차당뇨병조화당대사정상조비교차이유통계학의의(P=0.014).당대사정상자혈장망막소수평위(53.7±7.7)μg/L,당대사이상자위(33.5±6.0)μg/L,량자비교차이유통계학의의(P=0.023).다인소Logistic회귀분석현시혈장망막소수평하강시당대사이상적독립위험인소(P=0.027).결론 망막소가능재당대사이상적발생궤제중기도일정작용.
Objective To investigate the relation between plasma omentin and glycometabolism.Methods Eighty-five cases were divided into 3 groups by glucose tolerance test:diabetes mellitus group (42cases), impaired glucose regulation group (17 cases) and normal glucose regulation group (26 cases). The level of plasma omentin was assayed by ELISA. Results The level of plasma omentin was (53.7 ± 7.7),(40.7 ±9.9) and (30.6 ±5.3) μg/L in diabetes mellitus group, impaired glucose regulation group and normal glucose regulation group. There was significant difference among three groups (P= 0.049) and there was significant difference between diabetes mellitus group and normal glucose regulation group (P= 0.014).The level of plasma omentin in normal glycometabolism was (53.7 ± 7.7) μ g/L , and the level of plasma omentin in abnormal glycometabolism was (33.5 ± 6.0) μ g/L. There was significant difference between them(P = 0.023 ). Logistic analysis showed that the decline of plasma omentin was the independent risk factor ofglycometabolic disturbance (P= 0.027). Conclusion Omentin may play important roles in glycometabolic disturbance.
