CAJ | 학술논문

目的:探讨成分输血对急性失血患者酸碱平衡的影响.方法:对88例急性失血患者进行输血前及输血后定时血气分析监测,根据血气监测结果分析成分输血对酸碱平衡的影响.结果:观察期间14例患者存在其他影响酸碱平衡因素退出.纳入分析的74例中,44例输血前存在不同程度代谢性酸中毒的患者输血后26例酸中毒消失,17例减轻,1例略加重.74例患者中输血后发生输血相关性碱中毒24例,其24 h内新鲜冰冻血浆(FFP)平均用量2 063 ml,明显高于非碱中毒患者.输血相关性碱中毒的病例未使用酸性药物进行治疗,停止输血后13～48 h自动恢复.结论:急性失血患者输血前大部分存在程度不同的代谢性酸中毒,经有效止血、输血后多能缓解.成分输血对急性失血患者酸碱平衡的影响主要表现为代谢性碱中毒,代谢性酸中毒罕见.输血相关性碱中毒一般为自限性,停止输血后可自行恢复.
목적:탐토성분수혈대급성실혈환자산감평형적영향.방법:대88례급성실혈환자진행수혈전급수혈후정시혈기분석감측,근거혈기감측결과분석성분수혈대산감평형적영향.결과:관찰기간14례환자존재기타영향산감평형인소퇴출.납입분석적74례중,44례수혈전존재불동정도대사성산중독적환자수혈후26례산중독소실,17례감경,1례략가중.74례환자중수혈후발생수혈상관성감중독24례,기24 h내신선빙동혈장(FFP)평균용량2 063 ml,명현고우비감중독환자.수혈상관성감중독적병례미사용산성약물진행치료,정지수혈후13～48 h자동회복.결론:급성실혈환자수혈전대부분존재정도불동적대사성산중독,경유효지혈、수혈후다능완해.성분수혈대급성실혈환자산감평형적영향주요표현위대사성감중독,대사성산중독한견.수혈상관성감중독일반위자한성,정지수혈후가자행회복.
Objective:To investigate the acid-base balance influence of blood component transfusion on acute blood loss patients. Methods:We detected the blood gas analysis of 88 acute blood loss patients before and after blood component transfusion, to analyze the acid-base balance influence of blood component transfusion according to the blood gas analysis. Results:Fourteen patients were quit for the acid-base balance influence of other factors during the observation, Seventy-four patients were bring into the acid-base balance analysis; Among the forty-four patients with different degree acidosis before, Twenty-six patient's acidosis vanished after blood component transfusion,Seventeen patient's acidosis alleviated af-ter blood componenttransfusion, One patient's acidosis aggravated slightly after blood component transfusion;Twenty-four patients had blood transfusion relevent alkalosis in all seventy-four patients after transfusion, And their average usage amount of fresh frozen plasma (FFP) was 2 063 ml in 24 hours, It was much high than those patients without alkalosis; The patients with blood transfusion relevent alkalosis would be self-recovery within 13-48 hours after stop blood transfusion, without using any acidity medicine. Conclusion:Most of acute blood loss patients has different degree acidosis before blood transfusion. It would be relieved after effective hemostasis and blood transfusion; The principal influence of blood compo-nent transfusion on acute blood loss patients is alkalosis, and acidosis was very rare;The blood transfusion relevent alkalosis is self limited commonly. It would be self-recovery after hemostasis and blood transfusion.