目的 了解我国5个长寿地区高龄老人血浆硒、锰、铁、铜、锌微量元素含量水平及差异.方法 检测我国河南省夏邑县(110名)、湖北省钟祥市(111名)、湖南省麻阳县(60名)、广东省三水区(113名)、广西永福县(52名)5个长寿地区共446名高龄老人血浆硒、锰、铁、铜、锌微量元素含量,其中100～岁组208名,90～岁组238名,并比较不同性别、不同地区和不同年龄组微量元素含量的差异.结果 高龄老人血浆微量元素含量用中位数(四分位数间距)表示,硒为1.44(0.91)μmol/L,锰为0.54(0.94)μmol/L,铁为69.17(102.85)μmol/L,铜为20.19(8.73)μmol/L,锌为31.66(32.51)μmol/L.夏邑、钟祥、麻阳、三水、永福地区高龄老人血浆硒分别为1.46(0.66)、1.30(0.80)、1.06(0.51)、2.39(1.53)、1.35(0.55)μmol/L,锰分别为0.56(0.51)、1.40(1.11)、0.35(0.71)、0.44(0.55)、0.15(0.21)μmol/L,铁分别为86.77(86.87)、141.42(101.83)、38.88(36.28)、31.38(46.19)、79.64(75.34)μmol/L,铜分别为22.16(8.11)、19.46(9.26)、21.36(12.38)、18.12(6.74)、21.47(7.85)μmol/L,锌分别为36.85(26.18)、36.59(35.94)、39.98(56.91)、25.05(24.92)、16.74(16.81)μmol/L,不同地区微量元素含量差异有统计学意义(F值依次为29.76、38.75、47.18、11.51、13.47,P值均<0.05).不同性别组间血浆硒、锰、铁、铜、锌元素含量[男女硒含量分别为1.38(0.83)、1.45(0.91)μmol/L,锰含量分别为0.52(0.95)、0.54(0.91)μmol/L,铁含量分别为69.23(104.06)、69.11(101.05)μmol/L,铜含量分别为20.28(8.72)、20.06(8.76)μmol/L,锌含量分别为28.39(32.58)、31.85(34.26)μmol/L]差异无统计学意义(t_硒=-1.82,P=0.07;t_锰=0.64,P=0.52;t_铁=0.65,P=0.52;t_铜=-1.90,P=0.06;t_锌=-0.96,P=0.34).100～岁组血浆硒、铁、铜含量均高于90～岁组[硒分别为1.63(0.94)、1.30(0.82)μmol/L,铁分别为112.63(119.78)、60.13(58.43)μmol/L,铜分别为21.07(9.03)、18.81(8.86)μmol/L,F值依次为41.99、27.32、24.45,P值均小于0.01],血浆锰含量低于90～岁组[分别为0.44(0.76)、0.64(0.93)μmol/L,F=10.76,P<0.01],血浆锌含量差异无统计学意义[分别为3I.78(34.06)、31.11(33.85)μmol/L,F=1.32,P=0.25].结论 长寿地区高龄老人血浆硒、锰、铁、铜、锌微量元素含量水平较高,血浆硒、铁、铜含量随年龄增长而增加.
目的 瞭解我國5箇長壽地區高齡老人血漿硒、錳、鐵、銅、鋅微量元素含量水平及差異.方法 檢測我國河南省夏邑縣(110名)、湖北省鐘祥市(111名)、湖南省痳暘縣(60名)、廣東省三水區(113名)、廣西永福縣(52名)5箇長壽地區共446名高齡老人血漿硒、錳、鐵、銅、鋅微量元素含量,其中100～歲組208名,90～歲組238名,併比較不同性彆、不同地區和不同年齡組微量元素含量的差異.結果 高齡老人血漿微量元素含量用中位數(四分位數間距)錶示,硒為1.44(0.91)μmol/L,錳為0.54(0.94)μmol/L,鐵為69.17(102.85)μmol/L,銅為20.19(8.73)μmol/L,鋅為31.66(32.51)μmol/L.夏邑、鐘祥、痳暘、三水、永福地區高齡老人血漿硒分彆為1.46(0.66)、1.30(0.80)、1.06(0.51)、2.39(1.53)、1.35(0.55)μmol/L,錳分彆為0.56(0.51)、1.40(1.11)、0.35(0.71)、0.44(0.55)、0.15(0.21)μmol/L,鐵分彆為86.77(86.87)、141.42(101.83)、38.88(36.28)、31.38(46.19)、79.64(75.34)μmol/L,銅分彆為22.16(8.11)、19.46(9.26)、21.36(12.38)、18.12(6.74)、21.47(7.85)μmol/L,鋅分彆為36.85(26.18)、36.59(35.94)、39.98(56.91)、25.05(24.92)、16.74(16.81)μmol/L,不同地區微量元素含量差異有統計學意義(F值依次為29.76、38.75、47.18、11.51、13.47,P值均<0.05).不同性彆組間血漿硒、錳、鐵、銅、鋅元素含量[男女硒含量分彆為1.38(0.83)、1.45(0.91)μmol/L,錳含量分彆為0.52(0.95)、0.54(0.91)μmol/L,鐵含量分彆為69.23(104.06)、69.11(101.05)μmol/L,銅含量分彆為20.28(8.72)、20.06(8.76)μmol/L,鋅含量分彆為28.39(32.58)、31.85(34.26)μmol/L]差異無統計學意義(t_硒=-1.82,P=0.07;t_錳=0.64,P=0.52;t_鐵=0.65,P=0.52;t_銅=-1.90,P=0.06;t_鋅=-0.96,P=0.34).100～歲組血漿硒、鐵、銅含量均高于90～歲組[硒分彆為1.63(0.94)、1.30(0.82)μmol/L,鐵分彆為112.63(119.78)、60.13(58.43)μmol/L,銅分彆為21.07(9.03)、18.81(8.86)μmol/L,F值依次為41.99、27.32、24.45,P值均小于0.01],血漿錳含量低于90～歲組[分彆為0.44(0.76)、0.64(0.93)μmol/L,F=10.76,P<0.01],血漿鋅含量差異無統計學意義[分彆為3I.78(34.06)、31.11(33.85)μmol/L,F=1.32,P=0.25].結論 長壽地區高齡老人血漿硒、錳、鐵、銅、鋅微量元素含量水平較高,血漿硒、鐵、銅含量隨年齡增長而增加.
목적 료해아국5개장수지구고령노인혈장서、맹、철、동、자미량원소함량수평급차이.방법 검측아국하남성하읍현(110명)、호북성종상시(111명)、호남성마양현(60명)、광동성삼수구(113명)、엄서영복현(52명)5개장수지구공446명고령노인혈장서、맹、철、동、자미량원소함량,기중100～세조208명,90～세조238명,병비교불동성별、불동지구화불동년령조미량원소함량적차이.결과 고령노인혈장미량원소함량용중위수(사분위수간거)표시,서위1.44(0.91)μmol/L,맹위0.54(0.94)μmol/L,철위69.17(102.85)μmol/L,동위20.19(8.73)μmol/L,자위31.66(32.51)μmol/L.하읍、종상、마양、삼수、영복지구고령노인혈장서분별위1.46(0.66)、1.30(0.80)、1.06(0.51)、2.39(1.53)、1.35(0.55)μmol/L,맹분별위0.56(0.51)、1.40(1.11)、0.35(0.71)、0.44(0.55)、0.15(0.21)μmol/L,철분별위86.77(86.87)、141.42(101.83)、38.88(36.28)、31.38(46.19)、79.64(75.34)μmol/L,동분별위22.16(8.11)、19.46(9.26)、21.36(12.38)、18.12(6.74)、21.47(7.85)μmol/L,자분별위36.85(26.18)、36.59(35.94)、39.98(56.91)、25.05(24.92)、16.74(16.81)μmol/L,불동지구미량원소함량차이유통계학의의(F치의차위29.76、38.75、47.18、11.51、13.47,P치균<0.05).불동성별조간혈장서、맹、철、동、자원소함량[남녀서함량분별위1.38(0.83)、1.45(0.91)μmol/L,맹함량분별위0.52(0.95)、0.54(0.91)μmol/L,철함량분별위69.23(104.06)、69.11(101.05)μmol/L,동함량분별위20.28(8.72)、20.06(8.76)μmol/L,자함량분별위28.39(32.58)、31.85(34.26)μmol/L]차이무통계학의의(t_서=-1.82,P=0.07;t_맹=0.64,P=0.52;t_철=0.65,P=0.52;t_동=-1.90,P=0.06;t_자=-0.96,P=0.34).100～세조혈장서、철、동함량균고우90～세조[서분별위1.63(0.94)、1.30(0.82)μmol/L,철분별위112.63(119.78)、60.13(58.43)μmol/L,동분별위21.07(9.03)、18.81(8.86)μmol/L,F치의차위41.99、27.32、24.45,P치균소우0.01],혈장맹함량저우90～세조[분별위0.44(0.76)、0.64(0.93)μmol/L,F=10.76,P<0.01],혈장자함량차이무통계학의의[분별위3I.78(34.06)、31.11(33.85)μmol/L,F=1.32,P=0.25].결론 장수지구고령노인혈장서、맹、철、동、자미량원소함량수평교고,혈장서、철、동함량수년령증장이증가.
Objective To investigate the levels and differences of plasma selenium, manganese, iron,copper,zinc among oldest elderly in longevity areas in China. Methods 446 oldest elderly including 208 centenarians,238 aged 90 and over, who lived in Xiayi county of Henan province(110 persons), Zhongxiang city of Hubei province(111 persons), Mayang county of Hunan province (60 persons), Sanshui district of Guangdong province (113 persons), Yongfu county of Guangxi Zhuang autonomous region (52 persons) in China, were selected. The contents of plasma selenium, manganese, iron, copper, zinc were detected and compared among these elderly who were classified into different genders,different regions and different age groups. Results In oldest elderly, the median (inter-quartile range) of content of plasma selenium was I. 44 (0. 91) μmol/L, content of manganese was 0. 54 (0. 94) μmol/L, content of iron was 69. 17(102. 85) μmol/L, content of copper was 20. 19(8.73)μmol/L,eontent of zinc was 31.66(32. 51) μmol/L. Contents of plasma selenium of oldest elderly in Xiayi, Zhongxiang, Mayang, Sanshui, Yongfu region were 1.46(0.66),1.30(0.80),1.06(0.51) ,2. 39(1.53) and 1.35(0.55) μmol/L; contents of plasma manganese were 0. 56 (0. 51), 1. 40 (1. 11), 0. 35 (0. 71), 0. 44 (0. 55) and 0. 15 (0. 21) μmol/L; contents of plasma iron were 86. 77(86. 87) ,141.42(101.83) ,38.88(36. 28) ,31.38(46. 19) and 79.64(75.34) μmol/L;contents of plasma copper were 22. 16(8. 11) ,19. 46(9.26) ,21.36(12. 38), 18. 12(6. 74) and 21.47(7. 85) μmol/L;contents of plasma zinc were 36. 85(26. 18) ,36. 59(35.94) ,39. 98(56. 91) ,25.05 (24.92) and 16. 74(16. 81) μmol/L. Contents of plasma trace elements among oldest elderly in different longevity areas were significantly different(F values were 29.76,38. 75,47. 18,11. 51 and 13.47, P values were all less than 0. 05). Contents of plasma trace elements in different gender groups (contents of plasma selenium were 1. 38 (0. 83)μmol/L in male and 1.45 (0. 91) μmol/L in female; contents of plasma manganese were 0. 52(0. 95) and 0. 54(0. 91) μmol/L;contents of plasma iron were 69.23(104. 06) and 69. 11 (101. 05) μmol/L; contents of plasma copper were 20. 28 (8. 72) and 20. 06 (8. 76) μmol/L; contents of plasma zinc were 28. 39 (32. 58) and 31.85 (34. 26) μmol/L) were not significantly different (t_(Se) = -1. 82,P=0.07;t_(Mn) =0.64,P=0. 52;t_(Fe) =0. 65,P= 0.52;t_(Cu) = - 1.90,P= 0.06;t_(Zn)= -0.96,P= 0. 34). The contents of plasma selenium, iron, copper in centenarians were higher than those aged 90 and over (contents of plasma selenium were 1. 63 (0. 94) μmol/L and 1. 30 (0. 82) μmol/L, contents of plasma iron were 112.63(119. 78) and 60. 13(58.43) μmol/L,contents of plasma copper were 21.07(9.03)and 18. 81 (8. 86) μmol/L, F value were 41.99,27.32,24. 45, P values were less than 0. 01). Content of plasma manganese in centenarians was lower than those aged 90 and over (0. 44(0. 76)and 0. 64(0. 93) μmol/L, F = 10. 76, P < 0. 01). No significant differences were detected in plasma zinc between concentration and those aged 90 and over (31.78 (34. 06) and 31. 11 (33. 85) μmol/L; F = 1. 32, P = 0. 25). Conclusion The concentrations of plasma selenium, manganese, iron, copper and zinc were high in oldest elderly in the longevity areas. The contents of plasma selenium, iron, copper increased with age.
