中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2009年
12期
42-45,48
,共5页
何学酉%李钢%张旭%姜辉%赵连明%戴东曦%谢毅
何學酉%李鋼%張旭%薑輝%趙連明%戴東晞%謝毅
하학유%리강%장욱%강휘%조련명%대동희%사의
弱精了症%少精子症%雄激素类
弱精瞭癥%少精子癥%雄激素類
약정료증%소정자증%웅격소류
asthenospermia%oligospermia%androgens
目的 评估小剂量雄激素治疗男性少弱精子症的有效性和安全性.方法 采用多中心、随机、单盲、安慰剂对照的方法,对129例患者进行了疗程3月的临床研究.结果 治疗后,雄激素组患者的精液量、精子活力、精子活率、精子果糖、血睾酮升高,精子畸形率降低,差异有统计学意义:而安慰剂组患者的上述指标均无统计学差异.结论 小剂量雄激素补充治疗可显著提高少弱精子症患者的精液量、精子活力、精子活率、精浆果糖和血睾酮,降低精子畸形率.
目的 評估小劑量雄激素治療男性少弱精子癥的有效性和安全性.方法 採用多中心、隨機、單盲、安慰劑對照的方法,對129例患者進行瞭療程3月的臨床研究.結果 治療後,雄激素組患者的精液量、精子活力、精子活率、精子果糖、血睪酮升高,精子畸形率降低,差異有統計學意義:而安慰劑組患者的上述指標均無統計學差異.結論 小劑量雄激素補充治療可顯著提高少弱精子癥患者的精液量、精子活力、精子活率、精漿果糖和血睪酮,降低精子畸形率.
목적 평고소제량웅격소치료남성소약정자증적유효성화안전성.방법 채용다중심、수궤、단맹、안위제대조적방법,대129례환자진행료료정3월적림상연구.결과 치료후,웅격소조환자적정액량、정자활력、정자활솔、정자과당、혈고동승고,정자기형솔강저,차이유통계학의의:이안위제조환자적상술지표균무통계학차이.결론 소제량웅격소보충치료가현저제고소약정자증환자적정액량、정자활력、정자활솔、정장과당화혈고동,강저정자기형솔.
Objective To investigate the effect of a small quantity of androgen for the treatment of oligoasthenospermatism.Methods A total of 129 patients with oligo-asthenospermatism were enrolled in the multicentre,randomized,single-blind,placebo-controlled clinical trial with treatment by either testosterone undecanoate or placebo for 3 months.Results There were significant increase in semen volume,motility and survival rate of sperm,fructose level of seminal plasma and testosterone level of plasma,and decrease in teratosperm rate in patients of androgen group,whereas there were no significant differences in patients of placebo group.Conclusion Patients with oligoasthenospermatism can gain significant increase in semen volume,motility and survival rate of sperm,fructose level of seminal plasma and testosterone level of plasma,and decrease in teratosperm rate after the treatment of a small dose of androgen.
