中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
11期
15-16
,共2页
张宇%郑英斌%陆鹏%刘家霖%王建宇
張宇%鄭英斌%陸鵬%劉傢霖%王建宇
장우%정영빈%륙붕%류가림%왕건우
结肠癌%血清肿瘤相关物质
結腸癌%血清腫瘤相關物質
결장암%혈청종류상관물질
Colorectal carcinoma%Serum tumor associated material
目的 探讨结肠癌患者术前术后血清肿瘤相关物质(TAM)的表达变化及其对结肠癌的临床意义.方法 用TAM试剂盒检测36例结肠癌患者术前3d和术后2周的TAM表达,并对其与结肠癌生物学行为相关性进行分析.结果 结肠癌患者术前术后TAM浓度发生变化,TAM浓度的变化与结肠癌的淋巴结转移情况、浆膜类型有关,而与组织学类型、肿瘤体积大小无相关性.结论 TAM术前术后表达变化可以从总体上判断术后转移的淋巴结、周围组织浸润是否彻底清除,术后血清TAM表达降低多提示已彻底清除,升高多提示清除不彻底,变化不显著者应继续观察.
目的 探討結腸癌患者術前術後血清腫瘤相關物質(TAM)的錶達變化及其對結腸癌的臨床意義.方法 用TAM試劑盒檢測36例結腸癌患者術前3d和術後2週的TAM錶達,併對其與結腸癌生物學行為相關性進行分析.結果 結腸癌患者術前術後TAM濃度髮生變化,TAM濃度的變化與結腸癌的淋巴結轉移情況、漿膜類型有關,而與組織學類型、腫瘤體積大小無相關性.結論 TAM術前術後錶達變化可以從總體上判斷術後轉移的淋巴結、週圍組織浸潤是否徹底清除,術後血清TAM錶達降低多提示已徹底清除,升高多提示清除不徹底,變化不顯著者應繼續觀察.
목적 탐토결장암환자술전술후혈청종류상관물질(TAM)적표체변화급기대결장암적림상의의.방법 용TAM시제합검측36례결장암환자술전3d화술후2주적TAM표체,병대기여결장암생물학행위상관성진행분석.결과 결장암환자술전술후TAM농도발생변화,TAM농도적변화여결장암적림파결전이정황、장막류형유관,이여조직학류형、종류체적대소무상관성.결론 TAM술전술후표체변화가이종총체상판단술후전이적림파결、주위조직침윤시부철저청제,술후혈청TAM표체강저다제시이철저청제,승고다제시청제불철저,변화불현저자응계속관찰.
Objective To study the changes and expression of serum tumor associated material (TAM) before and after operation and its relationship with colorectal carcinoma.Methods The expression levels of TAM before and after operation in 36 cases of colorectal carcinoma were detected by TAM testing kit,and the relation between TAM expression and biological behavior of colorectal carcinoma was analyzed.Results The expression levels of TAM before and after operation were different and the changes was correlated with lymph nodes metastasis and invasive depth,but was not correlated with histologic typing or tumor volume.Conclusions The degree of elimination of metastatic lymph nodes and invasive depth can be infered through the changes of TAM before and after operation in colorectal carcinoma.