CAJ | 학술논문

目的评价壳聚糖(几丁糖)在输卵管介入再通术后防止复发性黏连的疗效.方法 309例患者随机分为对照组206例和试验组103例.对照组在输卵管阻塞介入复通术中常规注射松解液(α-糜蛋白酶、地塞米松、灭滴灵、庆大霉素)做术后防止黏连.试验组在术中常规注射松解液的基础上联合应用医用几丁糖防止黏连,术后通水治疗.随访观察两组病例松解输卵管的通畅情况.结果试验组,经子宫输卵管碘水造影阻塞190条,缺如10条;介入复通188条,再通率为98.9%;术后随访3个月通水达到无阻力180条,再黏连率4.26%(8/188).对照组输卵管造影确认堵塞390条,缺如22条,复通385条,复通率为98.7%,术后随访3个月,通水达到无阻力330条,再黏连率14.28%(55/385).两组术后3个月再黏连率有差异(P＜0.01).结论输卵管介入再通术后应用几丁糖能有效降低输卵管术后复发性黏连.
목적 평개각취당(궤정당)재수란관개입재통술후방지복발성점련적료효.방법 309례환자수궤분위대조조206례화시험조103례.대조조재수란관조새개입복통술중상규주사송해액(α-미단백매、지새미송、멸적령、경대매소)주술후방지점련.시험조재술중상규주사송해액적기출상연합응용의용궤정당방지점련,술후통수치료.수방관찰량조병례송해수란관적통창정황.결과 시험조,경자궁수란관전수조영조새190조,결여10조;개입복통188조,재통솔위98.9%;술후수방3개월통수체도무조력180조,재점련솔4.26%(8/188).대조조수란관조영학인도새390조,결여22조,복통385조,복통솔위98.7%,술후수방3개월,통수체도무조력330조,재점련솔14.28%(55/385).량조술후3개월재점련솔유차이(P＜0.01).결론 수란관개입재통술후응용궤정당능유효강저수란관술후복발성점련.
Objective To evaluate the efficacy of chitosan in preventing recurrence of fallopian tube obstruction.Methods A total of 309 cases was randomly divided into trial group(103 cases)and control group(206 cases).Cases of trial group were injected with chitosan especially and compared with the control group for preventing recurrence of fallopian tube obstruction after successful recanalization.A follow up examination of water insufflation was performed to assess the patency.Results In trial group,there were 190 obstructed fallopian tubes and 10 missing tubes,the recanalization rate was 98.9%(188/190).In control group,there were 390,and the recurrence rate was 4.26%(8/188).Fallopian obstructed tubes,and 22 missing tubes,the recanalization rate was 98.7%(385/390).After follow up of water insufflation 3 months,trial group had 180 tubes without resistance,and the recurrence rate was 4.26%(8/188),while control group had 330 tubes,and the recurrence rate was 4.28%(55/385).Recurrence rate of fallopian tube obstruction was significant difference between two groups(P＜0.01).Conclusion Chitosan infusion after interventional recanalization can reduce the recurrence of tube obstruction effectively.