中华普通外科杂志
中華普通外科雜誌
중화보통외과잡지
CHINESE JOURNAL OF GENERAL SURGERY
2011年
12期
977-980
,共4页
赵静%夏婷婷%贾永胜%魏松锋%赵文川
趙靜%夏婷婷%賈永勝%魏鬆鋒%趙文川
조정%하정정%가영성%위송봉%조문천
甲状腺肿瘤%预后%肿瘤分期
甲狀腺腫瘤%預後%腫瘤分期
갑상선종류%예후%종류분기
Thyroid neoplasms%Prognosis%Neoplasm staging
目的 分析甲状腺滤泡癌的临床生物学特征及影响预后的因素.方法 回顾性分析1970-1990年间天津市肿瘤医院收治的105例甲状腺滤泡癌患者的临床资料.结果 本组病例5、10和15年生存率分别为85.3％、76.7％和72.9％.≥45岁及＜45岁患者15年生存率分别为45.9％、89.8％.双侧腺叶及单侧腺叶发病患者15年生存率分别为50.0％、76.2％.有颈淋巴结转移及无颈淋巴结转移患者15年生存率分别为54.2％、79.2％.AJCC分期Ⅰ、Ⅱ、Ⅲ、Ⅳ期患者15年生存率分别为89.3％、70.0％、45.5％、35.3％.随访中11例发生远处器官转移,发生转移时间为术后1 ～33年,9例在发生转移后5年内死亡.17例发生局部复发,复发时间为术后3个月至34年,10例因复发死亡,占55.8％.结论 甲状腺滤泡癌患者的年龄、临床分期、双侧甲状腺叶发病和颈部淋巴结转移与预后关系密切.早期诊治和密切随访是改善患者预后、延长术后生存的主要手段.
目的 分析甲狀腺濾泡癌的臨床生物學特徵及影響預後的因素.方法 迴顧性分析1970-1990年間天津市腫瘤醫院收治的105例甲狀腺濾泡癌患者的臨床資料.結果 本組病例5、10和15年生存率分彆為85.3％、76.7％和72.9％.≥45歲及＜45歲患者15年生存率分彆為45.9％、89.8％.雙側腺葉及單側腺葉髮病患者15年生存率分彆為50.0％、76.2％.有頸淋巴結轉移及無頸淋巴結轉移患者15年生存率分彆為54.2％、79.2％.AJCC分期Ⅰ、Ⅱ、Ⅲ、Ⅳ期患者15年生存率分彆為89.3％、70.0％、45.5％、35.3％.隨訪中11例髮生遠處器官轉移,髮生轉移時間為術後1 ～33年,9例在髮生轉移後5年內死亡.17例髮生跼部複髮,複髮時間為術後3箇月至34年,10例因複髮死亡,佔55.8％.結論 甲狀腺濾泡癌患者的年齡、臨床分期、雙側甲狀腺葉髮病和頸部淋巴結轉移與預後關繫密切.早期診治和密切隨訪是改善患者預後、延長術後生存的主要手段.
목적 분석갑상선려포암적림상생물학특정급영향예후적인소.방법 회고성분석1970-1990년간천진시종류의원수치적105례갑상선려포암환자적림상자료.결과 본조병례5、10화15년생존솔분별위85.3％、76.7％화72.9％.≥45세급＜45세환자15년생존솔분별위45.9％、89.8％.쌍측선협급단측선협발병환자15년생존솔분별위50.0％、76.2％.유경림파결전이급무경림파결전이환자15년생존솔분별위54.2％、79.2％.AJCC분기Ⅰ、Ⅱ、Ⅲ、Ⅳ기환자15년생존솔분별위89.3％、70.0％、45.5％、35.3％.수방중11례발생원처기관전이,발생전이시간위술후1 ～33년,9례재발생전이후5년내사망.17례발생국부복발,복발시간위술후3개월지34년,10례인복발사망,점55.8％.결론 갑상선려포암환자적년령、림상분기、쌍측갑상선협발병화경부림파결전이여예후관계밀절.조기진치화밀절수방시개선환자예후、연장술후생존적주요수단.
Objective To investigate clinical biologic characteristics and factors that impact prognosis of patients with follicular thyroid carcinoma(FTC).Method Clinical data of 105 FTC patients treated surgically in the Department of Head& Neck,Tianjin Cancer Hospital from 1970 to 1990 was analyzed retrospectively.Results The overall 5-year,10-year and 15-year survival rates of these patients were 85.3％,76.7％ and 72.9％ respectively.The overall 15-year survival rates of patients ≥45 years and those ＜ 45 years were 45.9％,89.8％ respectively.The overall 15-year survival rates of patients with unilateral and bilateral carcinoma was 50.0％,76.2％ respectively.The overall 15-year survival rates of patients with neck lymph node metastasis and without were 54.2％,79.2％ respectively.The overall 15-year survival rates of patients at stage Ⅰ,stage Ⅱ,stageⅢ and stageⅣ were 89.3％,70.0％,45.5％ and 35.3％respectively.During the follow-up period,11 patients were diagnosed with distant metastasis from 1 year to 33 years after surgical treatment and 9 died of cancer within 5 years after diagnosis.Seventeen patients had local recurrence from 3 months to 34 years after surgery and 10 of these patients died of local recurrence.Conclusions The factors influencing prognosis of patients with FTC were age,clinical stage,bilateral carcinoma and neck lymph node metastasis,therefore early treatment and close following-up are essential to improve the prognosis of patients with FTC.
