中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2012年
1期
54-58
,共5页
李璐%陈长征%苏钰%冯超%郑红梅%邪怡桥%易莲芳
李璐%陳長徵%囌鈺%馮超%鄭紅梅%邪怡橋%易蓮芳
리로%진장정%소옥%풍초%정홍매%사이교%역련방
扫描图形视觉诱发电位%LogMAR视力%弱视%儿童%视觉发育
掃描圖形視覺誘髮電位%LogMAR視力%弱視%兒童%視覺髮育
소묘도형시각유발전위%LogMAR시력%약시%인동%시각발육
Sweep pattern visual evoked potential%LogMAR visual acuity%Amblyopia%Children%Visual development
背景 扫描图形视觉诱发电位(SPVEP)作为一种客观视功能检测技术,可被用于婴幼儿及合作度较差的成年人的客观视力测定.已有研究显示,振幅-视角对数( A-LogVA)回归方法可提高SPVEP推算视力的准确性. 目的 研究SPVEP在视觉发育期儿童中的应用,并比较两种不同的视力推断方法,即振幅-空间频率(A-SP)回归方法和A-LogVA回归方法在儿童,尤其是弱视儿童客观视力评估中的有效性和准确性.方法 选取3～12岁各种原因所致弱视儿童26例26眼为弱视组,同时选取与弱视组儿童年龄相匹配的正常儿童31人为正常组.检测其最佳矫正LogMAR视力,并使用视觉电生理仪检测SPVEP,选用0.99～12.89 cpd的10个不同空间频率正弦调制水平光栅连续刺激视网膜,结果经离散傅里叶分析后采用A-SP回归方法和A-LogVA回归方法计算SPVEP视力,对检测结果行相关性分析. 结果 在正常组,由A-SP回归方法和A-LogVA回归方法计算所得的SPVEP视力与LogMAR视力的相关系数分别为0.600 (P＜0.01)和0.733(P＜0.01),均数差异有统计学意义(F=113.173,P＜0.01).由A-SP回归方法所测得的SPVEP视力(A-SP视力)与LogMAR视力均数差值的绝对值为0.40±0.02,由A-LogVA回归方法所测得的SPVEP视力(A-LogVA视力)与LogMAR视力均数差值的绝对值为0.26±0.02,A-SP视力与A-LogVA视力均数差值的绝对值为0.14±0.02.在弱视组,由A-SP回归方法和A-LogVA回归方法计算所得的SPVEP视力与LogMAR视力的相关系数分别为0.134(P=0.515)和0.456(P＜0.05),均数差异有统计学意义(F=3.433,P＜0.05).A-SP视力与LogMAR视力均数差值的绝对值为0.07±0.05,A-LogVA视力与LogMAR视力均数差值的绝对值为0.12±0.05,A-SP视力与A-LogVA视力均数差值的绝对值为0.05±0.01.在不同视力段,SPVEP视力存在高估或低估现象. 结论 SPVEP可对正常视力及弱视儿童的客观视力进行评估,且A-LogVA回归方法推断所得客观视力更为准确.
揹景 掃描圖形視覺誘髮電位(SPVEP)作為一種客觀視功能檢測技術,可被用于嬰幼兒及閤作度較差的成年人的客觀視力測定.已有研究顯示,振幅-視角對數( A-LogVA)迴歸方法可提高SPVEP推算視力的準確性. 目的 研究SPVEP在視覺髮育期兒童中的應用,併比較兩種不同的視力推斷方法,即振幅-空間頻率(A-SP)迴歸方法和A-LogVA迴歸方法在兒童,尤其是弱視兒童客觀視力評估中的有效性和準確性.方法 選取3～12歲各種原因所緻弱視兒童26例26眼為弱視組,同時選取與弱視組兒童年齡相匹配的正常兒童31人為正常組.檢測其最佳矯正LogMAR視力,併使用視覺電生理儀檢測SPVEP,選用0.99～12.89 cpd的10箇不同空間頻率正絃調製水平光柵連續刺激視網膜,結果經離散傅裏葉分析後採用A-SP迴歸方法和A-LogVA迴歸方法計算SPVEP視力,對檢測結果行相關性分析. 結果 在正常組,由A-SP迴歸方法和A-LogVA迴歸方法計算所得的SPVEP視力與LogMAR視力的相關繫數分彆為0.600 (P＜0.01)和0.733(P＜0.01),均數差異有統計學意義(F=113.173,P＜0.01).由A-SP迴歸方法所測得的SPVEP視力(A-SP視力)與LogMAR視力均數差值的絕對值為0.40±0.02,由A-LogVA迴歸方法所測得的SPVEP視力(A-LogVA視力)與LogMAR視力均數差值的絕對值為0.26±0.02,A-SP視力與A-LogVA視力均數差值的絕對值為0.14±0.02.在弱視組,由A-SP迴歸方法和A-LogVA迴歸方法計算所得的SPVEP視力與LogMAR視力的相關繫數分彆為0.134(P=0.515)和0.456(P＜0.05),均數差異有統計學意義(F=3.433,P＜0.05).A-SP視力與LogMAR視力均數差值的絕對值為0.07±0.05,A-LogVA視力與LogMAR視力均數差值的絕對值為0.12±0.05,A-SP視力與A-LogVA視力均數差值的絕對值為0.05±0.01.在不同視力段,SPVEP視力存在高估或低估現象. 結論 SPVEP可對正常視力及弱視兒童的客觀視力進行評估,且A-LogVA迴歸方法推斷所得客觀視力更為準確.
배경 소묘도형시각유발전위(SPVEP)작위일충객관시공능검측기술,가피용우영유인급합작도교차적성년인적객관시력측정.이유연구현시,진폭-시각대수( A-LogVA)회귀방법가제고SPVEP추산시력적준학성. 목적 연구SPVEP재시각발육기인동중적응용,병비교량충불동적시력추단방법,즉진폭-공간빈솔(A-SP)회귀방법화A-LogVA회귀방법재인동,우기시약시인동객관시력평고중적유효성화준학성.방법 선취3～12세각충원인소치약시인동26례26안위약시조,동시선취여약시조인동년령상필배적정상인동31인위정상조.검측기최가교정LogMAR시력,병사용시각전생리의검측SPVEP,선용0.99～12.89 cpd적10개불동공간빈솔정현조제수평광책련속자격시망막,결과경리산부리협분석후채용A-SP회귀방법화A-LogVA회귀방법계산SPVEP시력,대검측결과행상관성분석. 결과 재정상조,유A-SP회귀방법화A-LogVA회귀방법계산소득적SPVEP시력여LogMAR시력적상관계수분별위0.600 (P＜0.01)화0.733(P＜0.01),균수차이유통계학의의(F=113.173,P＜0.01).유A-SP회귀방법소측득적SPVEP시력(A-SP시력)여LogMAR시력균수차치적절대치위0.40±0.02,유A-LogVA회귀방법소측득적SPVEP시력(A-LogVA시력)여LogMAR시력균수차치적절대치위0.26±0.02,A-SP시력여A-LogVA시력균수차치적절대치위0.14±0.02.재약시조,유A-SP회귀방법화A-LogVA회귀방법계산소득적SPVEP시력여LogMAR시력적상관계수분별위0.134(P=0.515)화0.456(P＜0.05),균수차이유통계학의의(F=3.433,P＜0.05).A-SP시력여LogMAR시력균수차치적절대치위0.07±0.05,A-LogVA시력여LogMAR시력균수차치적절대치위0.12±0.05,A-SP시력여A-LogVA시력균수차치적절대치위0.05±0.01.재불동시력단,SPVEP시력존재고고혹저고현상. 결론 SPVEP가대정상시력급약시인동적객관시력진행평고,차A-LogVA회귀방법추단소득객관시력경위준학.
Background Sweep pattern visual evoked potential(SPVEP) acuity,as an objective detective technique of visual function,can be used to measure visual acuity in children and uncooperative adults.Recent studies have shown that the amplitude-logarithm of the visual angle (A-LogVA) function regression method was more accurate than the amplitude-spatial frequency (A-SP)function regression method in evaluating SPVEP acuity. Objective This study was to explore the clinical use of SPVEP acuity in visual developing children and compare the evaluating the SPVEP acuity of children between A-SP function regression method and A-LogVA function regression method.Methods Twenty-six eyes of 26 asthenopic children with age range of 3-12 years and 31 age-matched normal children were enrolled in this study.SPVEP acuity was recorded with GT-2000 NV ( GUOTE MEDICAL APPARATUS LTD,China) using sinusoidally modulated horizontal gratings of 10 different spatial frequencies from 0.99 to 12.89 cpd as stimulus.The responses were averaged and displayed through discrete Fourier transformations (DFT) on the monitor display.SPVEP acuity was estimated by using both the SPVEP A-SP function regression method and the SPVEP A-LogVA function regression method.The LogMAR chart was used to acquire LogMAR visual acuity.Results In the normal group,the correlation coefficient between LogMAR visual acuity and acuity calculated by the A-SP function regression method was 0.600 (P＜0.01).The correlation coefficient between LogMAR visual acuity and acuity calculated by the A-LogVA function regression method was 0.733 ( P＜0.01 ).The ANOVA of the LogMAR acuity and the SPVEP acuity calculated from the A-SP function regression method and A-LogVA function regression method were 113.173 (P＜0.01 ),which indicated that there were significant difference among all of subjects.The differences of the mean values of LogMAR visual acuity and the SPVEP acuity calculated from the A-SP function regression method and A-LogVA function regression method were respectively 0.40±0.02,0.26 ±0.02 and 0.14 ± 0.02.In the amblyopia group,the correlation coefficient between LogMAR visual acuity and acuity calculated by the A-SP function regression method was 0.134 (P =0.515 ).The correlation coefficient between LogMAR visual acuity and acuity calculated by the A-LogVA function regression method was 0.456 ( P＜0.05 ).The ANOVA of the LogMAR acuity and the SPVEP acuity calculated from the A-SP function regression method and A-LogVA function regression method were 3.433 (P＜0.05),indicating that there were significant difference among all of subjects.The differences of the mean values of LogMAR visual acuity and the SPVEP acuity calculated from the A-SP function regression method and A-LogVA function regression method were 0.07±0.05,0.12±0.05 and 0.05 ±0.01 respectively.Conclusions SPVEP can evaluate the visual acuity in children,although SPVEP acuity may overestimate or underestimate acuity in comparison with different LogMAR visual acuities.The amplitude-LogVA function regression method is more accurate in extrapolating SPVEP acuity.
