CAJ | 학술논문

随着小动物成像技术的发展,活体小动物非侵袭性成像在临床前研究中发挥着越来越重要的作用.本研究围绕可见光成像、核素成像、核磁共振成像、计算机断层摄影成像和超声成像等5种小动物成像技术,总结其特点及主要应用,比较各种技术的优势和劣势,并讨论小动物活体成像技术的发展趋势.
수착소동물성상기술적발전,활체소동물비침습성성상재림상전연구중발휘착월래월중요적작용.본연구위요가견광성상、핵소성상、핵자공진성상、계산궤단층섭영성상화초성성상등5충소동물성상기술,총결기특점급주요응용,비교각충기술적우세화열세,병토론소동물활체성상기술적발전추세.
With the development of small animal imaging technology, non-invasive imaging in small living animal models has gained increasing importance in pre-clinical research.Five kinds of small animal imaging technology, including optical imaging, PET/SPECT, MRI, CT and ultrasound imaging, were reviewed from the aspects of their characteristics and main applications.Meanwhile, the advantages and limitations of them were summarized.The trends of small living animal imaging technology were discussed as well.