中国循证医学杂志
中國循證醫學雜誌
중국순증의학잡지
CHINESE JOURNAL OF EVIDENCE-BASED MEDICINE
2010年
4期
488-491
,共4页
中医药%系统评价%Meta分析%异质性
中醫藥%繫統評價%Meta分析%異質性
중의약%계통평개%Meta분석%이질성
Traditional Chinese Medicine%Systematic review%Meta-analysis%Heterogeneity
目的 对国内发表的中医药系统评价/Meta分析中的异质性问题进行分析,了解异质性的来源、类别及严重程度,探讨中医药系统评价中异质性的正确处理方法 .方法 计算机检索CBM、CNKI、VIP等中文数据库及手检<中国循证医学杂志>,检索截止时间为2008年.由两位研究者按照纳入与排除标准独立提取资料并对有关异质性的问题进行评价.若遇分歧,讨论解决.结果 共纳入115个中医药系统评价/Meta分析,涉及17类疾病.其中以心血管疾病最多(36,31.3%).有41个(35.65%)中医药系统评价混合纳入了两种或两种以上设计类型的原始研究;有62个(53.91%)系统评价所纳入研究的干预措施不一致,有60个(52.17%)系统评价中的对照措施不一致;另有10个(8.7%)系统评价的异质性处理方法 不当.结论 中医药系统评价/Meta分析中异质性问题普遍存在,尤以临床异质性最为突出.异质性问题处置不当,会直接影响中医药系统评价的质量.
目的 對國內髮錶的中醫藥繫統評價/Meta分析中的異質性問題進行分析,瞭解異質性的來源、類彆及嚴重程度,探討中醫藥繫統評價中異質性的正確處理方法 .方法 計算機檢索CBM、CNKI、VIP等中文數據庫及手檢<中國循證醫學雜誌>,檢索截止時間為2008年.由兩位研究者按照納入與排除標準獨立提取資料併對有關異質性的問題進行評價.若遇分歧,討論解決.結果 共納入115箇中醫藥繫統評價/Meta分析,涉及17類疾病.其中以心血管疾病最多(36,31.3%).有41箇(35.65%)中醫藥繫統評價混閤納入瞭兩種或兩種以上設計類型的原始研究;有62箇(53.91%)繫統評價所納入研究的榦預措施不一緻,有60箇(52.17%)繫統評價中的對照措施不一緻;另有10箇(8.7%)繫統評價的異質性處理方法 不噹.結論 中醫藥繫統評價/Meta分析中異質性問題普遍存在,尤以臨床異質性最為突齣.異質性問題處置不噹,會直接影響中醫藥繫統評價的質量.
목적 대국내발표적중의약계통평개/Meta분석중적이질성문제진행분석,료해이질성적래원、유별급엄중정도,탐토중의약계통평개중이질성적정학처리방법 .방법 계산궤검색CBM、CNKI、VIP등중문수거고급수검<중국순증의학잡지>,검색절지시간위2008년.유량위연구자안조납입여배제표준독립제취자료병대유관이질성적문제진행평개.약우분기,토론해결.결과 공납입115개중의약계통평개/Meta분석,섭급17류질병.기중이심혈관질병최다(36,31.3%).유41개(35.65%)중의약계통평개혼합납입료량충혹량충이상설계류형적원시연구;유62개(53.91%)계통평개소납입연구적간예조시불일치,유60개(52.17%)계통평개중적대조조시불일치;령유10개(8.7%)계통평개적이질성처리방법 불당.결론 중의약계통평개/Meta분석중이질성문제보편존재,우이림상이질성최위돌출.이질성문제처치불당,회직접영향중의약계통평개적질량.
Objective To analyze the heterogeneity of systematic reviews (SRs)/Meta-analysis on traditional Chinese medicine (TCM),and explore strategies for addressing heterogeneity correctly during the process of conducting TCM related to systematic reviews (SRs).Methods Both electronic and hand searches were used to identify TCM SRs in CBM,CNKI,VIP database,and Chinese Journal of Evidence-Based Medicine.Two researchers performed data extracting and heterogeneity evaluation independently.Results A total of 115 TCM SRs were included,involving 17 types of diseases,among which the cardiovascular and cerebrovascular diseases were the most addressed (n=36,31.30%).There were 35.65% (n=41) of SRs which integrated two or more types of studies;interventions of the included studies were inconsistent in 53.91% (n=62) of TCM SRs;control groups of the included studies were completely different in 60 (52.17%) SRs;and 8.7% (n=10) of SRs failed to investigate heterogeneity in the process of synthesis analysis.Conclusion The heterogeneity is common in TCM related to SRs,and the most addressed is clinical heterogeneity.Addressing heterogeneity incorrectly would downgrade the quality of TCM related to SRs.
