CAJ | 학술논문

目的观察聚维酮碘乳膏外敷防治化疗药物外渗性损伤的效果.方法将224例应用化疗药物治疗药物外渗性损伤患者随机分为治疗组及对照组各112例,治疗组采用聚维酮碘乳膏纱布外敷,对照组采用2%普鲁卡因局部封闭、冰敷、外涂多磺酸粘多糖乳膏、50%硫酸镁湿敷等常规治疗.比较两组临床疗效.结果治疗组总有效率92.9%,对照组总有效率77.6%,两组疗效比较差异有统计学意义(χ2=11.518,P＜0.05).结论聚维酮碘乳膏外敷防治化疗药物外渗性损伤的效果较好.
목적 관찰취유동전유고외부방치화료약물외삼성손상적효과.방법 장224례응용화료약물치료약물외삼성손상환자수궤분위치료조급대조조각112례,치료조채용취유동전유고사포외부,대조조채용2%보로잡인국부봉폐、빙부、외도다광산점다당유고、50%류산미습부등상규치료.비교량조림상료효.결과 치료조총유효솔92.9%,대조조총유효솔77.6%,량조료효비교차이유통계학의의(χ2=11.518,P＜0.05).결론 취유동전유고외부방치화료약물외삼성손상적효과교호.
Objective To observe the effect of povidone-iodine cream to treat and prevent from the chemotherapy extravasation injury. Methods 224 cases with chemotherapy drugs treatment were divided into treatment group and control group. The treatment group was treated with povidone-iodine gauze topical cream,the control group was treated with the conventional methods such as partial closure of 2% procaine, ice application and hirudoid externally application, 50% magnesium sulfate wet covering and so on. Ridit analysis has been applied to compare the clinical efficacy of different group. Results The total effective rate was 92.9% in the treatment group, while the total efficiency rate of 77.6% in the control group. The effective rate was significantly different between the two groups (χ2 = 11.518, P ＜ 0. 05). Conclusions Povidone-iodine cream has better effectiveness to control the chemotherapy extravasation injury compared with the conventional methods.