CAJ | 학술논문

目的探讨前列腺炎患者血清总前列腺特异抗原(TPSA)、游离型前列腺特异性抗原(FPSA) 及游离型前列腺特异性抗原/总前列腺特异抗原(FPSA/TPSA)比值与前列腺液白细胞(WBC)的相关性.方法通过化学发光法测定205例前列腺炎患者血清TPSA、FPSA、FPSA/TPSA比值,再与前列腺液(EPS)镜检WBC含量作比较,分析不同EPS中WBC含量与血清TPSA、FPSA、FPSA/TPSA比值的关系,以及前列腺炎治疗前后血清TPSA、FPSA、FPSA/TPSA比值的变化,来确定两者的相关性,试验同时设对照组40例.结果前列腺炎较严重组(WBC+++～++++)血清FPSA、TPSA及FPSMTPSA比值与前列腺炎较轻组(WBC+～++)及正常对照组差异均有显著性(P＜0.05),前列腺炎治疗好转前后血清TPSA、FPSA、FPSA/TPSA比值对比有显著性差异(P＜0.05).结论前列腺炎可以导致血清TPSA、FPSA及FPSA/TPSA升高,这种升高与EPS中WBC的含量呈正相关,血清TPSA、FPSA及FPSA/TPSA升高也可以作为前列腺炎疗效判断的一项指标.
목적 탐토전렬선염환자혈청총전렬선특이항원(TPSA)、유리형전렬선특이성항원(FPSA) 급유리형전렬선특이성항원/총전렬선특이항원(FPSA/TPSA)비치여전렬선액백세포(WBC)적상관성.방법 통과화학발광법측정205례전렬선염환자혈청TPSA、FPSA、FPSA/TPSA비치,재여전렬선액(EPS)경검WBC함량작비교,분석불동EPS중WBC함량여혈청TPSA、FPSA、FPSA/TPSA비치적관계,이급전렬선염치료전후혈청TPSA、FPSA、FPSA/TPSA비치적변화,래학정량자적상관성,시험동시설대조조40례.결과전렬선염교엄중조(WBC+++～++++)혈청FPSA、TPSA급FPSMTPSA비치여전렬선염교경조(WBC+～++)급정상대조조차이균유현저성(P＜0.05),전렬선염치료호전전후혈청TPSA、FPSA、FPSA/TPSA비치대비유현저성차이(P＜0.05).결론 전렬선염가이도치혈청TPSA、FPSA급FPSA/TPSA승고,저충승고여EPS중WBC적함량정정상관,혈청TPSA、FPSA급FPSA/TPSA승고야가이작위전렬선염료효판단적일항지표.
Objoetive To investigate the correlation of serum TPSA,FPSA,and FPSA/TPSA with WBC content in expressed prostatic secretion(EPS)in patients with prostatitis.Methods Serum TPSA,FPSA.and FPSA/TPSA were detected with ECLIA technique in 205 patients and then were compared with the WBC content in EPS.The correlation of WBC in EPS with serum TPSA,FPSA,and FPSA/TPSA was analyzed.40 normal individuals were used as control.Results Serum TPSA,FPSA,and FPSA/TPSA differed significantly between the prostatitis group and the control group(P＜0.05) and between the group with higher WBC content and the group with lower WBC content(P＜0.05). and they also differed significantly after treatment.(P＜0.05). Conclusions Prostatitis may lead to an increase in serum TPSA,FPSA,and FPSA/TPSA and this change is related with the WBC content in EPS.The increased serum TPSA,FPSA,and FPSA/TPSA can be used as a index for of judging the efficacy of treatment.