CAJ | 학술논문

目的评价氩氦刀(ASCS)联合肝动脉导管化疗栓塞术(TACE)治疗中晚期肝癌的疗效.方法氩氦刀经皮穿刺冷冻消融治疗76例中晚期肝癌患者81个病灶(肿瘤直径501-15.0 cm),ASCS前后联合TACE治疗,随访观察治疗效果、并发症和患者生存情况.结果 ASCS操作均顺利完成,并发症6.58%(5/76),包括皮肤冻伤2例,胆漏1例,腹腔出血2例.TACE无并发症.随访16-62个月,随访率92.1%,6个月、1年、3年生存率分别为98.6%、72.9%和30.6%.结论 ASCS联合TACE能发挥互补增效作用,是治疗中晚期肝癌的一种有效方法.
목적 평개아양도(ASCS)연합간동맥도관화료전새술(TACE)치료중만기간암적료효.방법 아양도경피천자냉동소융치료76례중만기간암환자81개병조(종류직경501-15.0 cm),ASCS전후연합TACE치료,수방관찰치료효과、병발증화환자생존정황.결과 ASCS조작균순리완성,병발증6.58%(5/76),포괄피부동상2례,담루1례,복강출혈2례.TACE무병발증.수방16-62개월,수방솔92.1%,6개월、1년、3년생존솔분별위98.6%、72.9%화30.6%.결론 ASCS연합TACE능발휘호보증효작용,시치료중만기간암적일충유효방법.
Objective To assess the local treatment etficacy of argon super cryosurgery system (ASCS)therapy in combination with transeatheter arteria chemoembolization (TACE) for large hepatocellular carcinoma (HCC). Methods Eighty - one lesions ranged 5.1 - 15.0 cm in diameter in 76 patients with HCC were trea-ted by ASCS in combination with TACE. TACE was applied pre - or post - ASCS. Patients' survival rate and lesions' necrosis were evaluated. Results The procedures were performed successfully in all patients. Of 76 patients with HCC, the post - ASCS complication rate was 6.58% ( 5/76 ), TACE were carried out without any complication. The follow - up period ( mean, 38 months). The level of serum AFP was declined in 89. 3% of the patients. Six cases (8.6%) achieved a complete response (CR) ,and 63 (90%) achieved a partial response (PR). The effective rate (CR + PR) was 98.6%. The patients' survival rates were 98.6%at 6 months,72.9% at one year, and 30.6% at 3 years, respectively. Conclusion The results of this study suggest that ASCS plus TACE is an effective mini - invasive combined therapy and can be a choice of treat-ment regime for the large HCC in properly selective patients.