CAJ | 학술논문

采用湿法消解对不同品质的怀地黄样品进行处理,利用ICP-MS测定不同品质生(干)怀地黄与相应水蒸法炮制熟地黄中多种金属元素含量.结果表明,不同品质地黄及其炮制加工的熟地黄之间金属元素含量无明显差异;熟地黄中含有Zn,Cu,Cr,Fe,Mn,Sn,Ni,Mo,Co等人体必需的多种微量元素,其中Ca,Fe,Al,Zn,Cu含量较高;不同品质生地黄中对人体健康有利的金属元素含量相对低于其相应品质炮制产物熟地黄.地黄中含有的Co,Ni,Cr,Mn等虽为人体所必需,但超过一定最对人体会产生毒害作用;而Pb等则是对人体有害的微量元素,应该在地黄炮制工艺中注意控制或降低消除此类元素.不同品质地黄中金属元素含量的测定可以为地黄及其炮制加工产物的综合评价提供有益参考.
채용습법소해대불동품질적부지황양품진행처리,이용ICP-MS측정불동품질생(간)부지황여상응수증법포제숙지황중다충금속원소함량.결과표명,불동품질지황급기포제가공적숙지황지간금속원소함량무명현차이;숙지황중함유Zn,Cu,Cr,Fe,Mn,Sn,Ni,Mo,Co등인체필수적다충미량원소,기중Ca,Fe,Al,Zn,Cu함량교고;불동품질생지황중대인체건강유리적금속원소함량상대저우기상응품질포제산물숙지황.지황중함유적Co,Ni,Cr,Mn등수위인체소필수,단초과일정최대인체회산생독해작용;이Pb등칙시대인체유해적미량원소,응해재지황포제공예중주의공제혹강저소제차류원소.불동품질지황중금속원소함량적측정가이위지황급기포제가공산물적종합평개제공유익삼고.
The Huai radix rehmanniae at different grades was pretreated by wet digestion, and then the metal elements in the ra-dix rehmanniae and the prepared sample by steaming method were determined using ICP-MS. The results indicate that there is no obvious difference in the metal elements between the different grades and between the dried radix rehmanniae and its correspond-ing prepared product. There are elements Zn, Cu, Cr, Fe, Mn, Sn, Ni, Mo, Go, etc. in radix rehmanniae, among which the contents of Ca, Fe, Al, Zn and Cu are higher; the metal elements beneficial to human body in dried radix rehmanniae are relative lower than that in the prepared one. The elements such as Co, Ni, Cr, Mn, etc. in radix rehmanniae have poison effects on hu-man body when their contents are more than a certain threshold value, although they are human essential elements. Element Pb is harmful to human body, which should be controlled and reduced/eliminated in the processing procedure. The determination and comparison of the metal elements in radix rehrnarmiae at different grades can provide useful information about the compre-hensive evaluation of dried radix rehmanniae and their prepared products.