中华超声影像学杂志
中華超聲影像學雜誌
중화초성영상학잡지
CHINESE JOURNAL OF ULTRASONOGRAPHY
2011年
3期
222-225
,共4页
裴小青%刘隆忠%左菲菲%郑玮%李毓红%韩峰%李安华
裴小青%劉隆忠%左菲菲%鄭瑋%李毓紅%韓峰%李安華
배소청%류륭충%좌비비%정위%리육홍%한봉%리안화
超声检查%微气泡%癌,肝细胞%新生血管化,病理性
超聲檢查%微氣泡%癌,肝細胞%新生血管化,病理性
초성검사%미기포%암,간세포%신생혈관화,병이성
Ultrasonography%Microbubbles%Carcinoma,hepatocellular%Neovascularization,pathologic
目的 探讨肝细胞癌(hepatocellular carcinoma,HCC)的超声造影(contrast-ehhanced ultrasonography,CEUS)定量参数与HCC内新生动脉的关系.方法 对115例HCC的CEUS图像进行脱机分析和免疫组化染色,获得感兴趣区的灌注曲线及CEUS定量参数:峰值强度(maximum of intensity,IMAX)、上升时间(rise time,RT)、达峰时间(time to peak,TTP)、平均渡越时间(mean trasit time corresponding to the center of grayity,mTT)、上升斜率(rise slope,RS)和始消时间(washout time,WT).获得82例HCC内的非成对动脉数,将CEUS定量参数和非成对动脉数进行统计学分析.结果 HCC中非成对动脉数与RT、TTP、RS呈中度相关,r分别为-0.446,-0.432,0.431(P＜0.05),与IMAX和WT呈弱相关,r分别为0.303和0.285(P＜0.05).结论 HCC内的新生动脉是HCC动脉相增强的病理生理基础,CEUS定量参数反映了肿瘤灌注情况,与HCC中的非成对动脉数有关.
目的 探討肝細胞癌(hepatocellular carcinoma,HCC)的超聲造影(contrast-ehhanced ultrasonography,CEUS)定量參數與HCC內新生動脈的關繫.方法 對115例HCC的CEUS圖像進行脫機分析和免疫組化染色,穫得感興趣區的灌註麯線及CEUS定量參數:峰值彊度(maximum of intensity,IMAX)、上升時間(rise time,RT)、達峰時間(time to peak,TTP)、平均渡越時間(mean trasit time corresponding to the center of grayity,mTT)、上升斜率(rise slope,RS)和始消時間(washout time,WT).穫得82例HCC內的非成對動脈數,將CEUS定量參數和非成對動脈數進行統計學分析.結果 HCC中非成對動脈數與RT、TTP、RS呈中度相關,r分彆為-0.446,-0.432,0.431(P＜0.05),與IMAX和WT呈弱相關,r分彆為0.303和0.285(P＜0.05).結論 HCC內的新生動脈是HCC動脈相增彊的病理生理基礎,CEUS定量參數反映瞭腫瘤灌註情況,與HCC中的非成對動脈數有關.
목적 탐토간세포암(hepatocellular carcinoma,HCC)적초성조영(contrast-ehhanced ultrasonography,CEUS)정량삼수여HCC내신생동맥적관계.방법 대115례HCC적CEUS도상진행탈궤분석화면역조화염색,획득감흥취구적관주곡선급CEUS정량삼수:봉치강도(maximum of intensity,IMAX)、상승시간(rise time,RT)、체봉시간(time to peak,TTP)、평균도월시간(mean trasit time corresponding to the center of grayity,mTT)、상승사솔(rise slope,RS)화시소시간(washout time,WT).획득82례HCC내적비성대동맥수,장CEUS정량삼수화비성대동맥수진행통계학분석.결과 HCC중비성대동맥수여RT、TTP、RS정중도상관,r분별위-0.446,-0.432,0.431(P＜0.05),여IMAX화WT정약상관,r분별위0.303화0.285(P＜0.05).결론 HCC내적신생동맥시HCC동맥상증강적병리생리기출,CEUS정량삼수반영료종류관주정황,여HCC중적비성대동맥수유관.
Objective To explore the relationships between the quantitative parameters for contrastenhanced ultrasonography(CEUS) in hepatocellular carcinoma (HCC) and arteries in neoangiogenesis.Methods One hundred and fifteen HCCs in CEUS were analyzed off-line with dynamic vascular curve of ImageArena and immunohistochemical stained in the tissue slices.Parameters including maximum of intensity(IMAX),rise time(RT),time to peak(TTP),mean trasit time corresponding to the center of gravity(mTT) ,rise slope(RS) and washout time(WT) were analyzed by statistics.Unpaired arteries(UAs)of 82 HCC cases were succesfully stained.Results The number of UAs had moderate correlation with RT (r = - 0.446),TTP (r = - 0.432) and RS (r = 0.431) (P ＜ 0.05),and it had mild correlation with IMAX (r = 0.303) ,WT (r = 0.285) (P ＜0.05).Conclusions Neoangiogenesis is a functional adaptation to altered vascular dynamics.Quantitative parameters of CEUS,reflecting hemodynamics of tumors,are correlated with UAs.
