CAJ | 학술논문

目的探讨成都市城市人群中慢性肾脏病(CKD)的患病情况和相关危险因素,以及危险人群CKD的患病情况.方法通过对成都市常住居民中的铁路职工健康体检,进行CKD及相关危险因素的问卷调查(既往史、吸烟、饮酒等)、体格检查(血压、身高和体质量等)和相关血尿指标检测(血糖、血脂、血尿酸、血肌酐、尿微量白蛋白/肌酐比值、尿常规等),了解成都市城市人群CKD的患病情况及相关危险因素,以及危险人群CKD的患病情况.结果在5326例资料完整的人群中,经过人口年龄和性别构成比校正后,白蛋白尿的患病率为11.54％,肾功能下降的患病率为5.54％,血尿的患病率为3.87％.该人群中CKD的患病率为18.32％,知晓率为1.93％.3098例高血压、糖尿病和高血脂人群中,白蛋白尿的患病率分别为23.79％、28.00％、14.08％;肾功能下降的患病率分别为4.76％、4.53％、3.26％;血尿的患病率分别为2.94％、3.20％、2.37％.多因素Logistic回归提示,女性、高血压、糖尿病、高血脂和高体质量指数是白蛋白尿的独立危险因素;女性、年龄、高尿酸和高血压是肾功能下降的独立危险因素,丽饮酒与肾功能下降呈负相关;女性和年龄是血尿的独立危险因素.结论成都市城市人群中,CKD的患病率较高,知晓率较已报道的城市人群低.相关危险因素包括年龄、女性、糖尿病、高血压、高血脂、高尿酸、高体质量指数等.控制代谢性疾病的发生发展可减少CKD的发生.
목적 탐토성도시성시인군중만성신장병(CKD)적환병정황화상관위험인소,이급위험인군CKD적환병정황.방법 통과대성도시상주거민중적철로직공건강체검,진행CKD급상관위험인소적문권조사(기왕사、흡연、음주등)、체격검사(혈압、신고화체질량등)화상관혈뇨지표검측(혈당、혈지、혈뇨산、혈기항、뇨미량백단백/기항비치、뇨상규등),료해성도시성시인군CKD적환병정황급상관위험인소,이급위험인군CKD적환병정황.결과 재5326례자료완정적인군중,경과인구년령화성별구성비교정후,백단백뇨적환병솔위11.54％,신공능하강적환병솔위5.54％,혈뇨적환병솔위3.87％.해인군중CKD적환병솔위18.32％,지효솔위1.93％.3098례고혈압、당뇨병화고혈지인군중,백단백뇨적환병솔분별위23.79％、28.00％、14.08％;신공능하강적환병솔분별위4.76％、4.53％、3.26％;혈뇨적환병솔분별위2.94％、3.20％、2.37％.다인소Logistic회귀제시,녀성、고혈압、당뇨병、고혈지화고체질량지수시백단백뇨적독립위험인소;녀성、년령、고뇨산화고혈압시신공능하강적독립위험인소,려음주여신공능하강정부상관;녀성화년령시혈뇨적독립위험인소.결론 성도시성시인군중,CKD적환병솔교고,지효솔교이보도적성시인군저.상관위험인소포괄년령、녀성、당뇨병、고혈압、고혈지、고뇨산、고체질량지수등.공제대사성질병적발생발전가감소CKD적발생.
Objective To investigate the prevalence and risk factors of chronic kidney disease (CKD) in Chengdu urban population and the prevalence of CKD in risk population.Methods Questionnaire (anamnesis,smoking,drink) of risk factors of CKD and somatoscopy (blood pressure,body height and body weight) were caried out in railman of Chengdu urban.Their blood and urine indicators (blood sugar,blood lipid,blood uric acid,blood creatinine,uromicroprotein/creatinine ratio,routine urine examination,etc) were measured.The prevalence and risk factors of CKD in Chengdu urban population and the prevalence of CKD in risk population were elucidated.Results Eligible data of 5326 subjects were enrolled in the study.After the adjustment of age and gender component,the prevalence of albuminuria was 11.54％,reduced eGFR was 5.54％,hematuria was 3.87％,and CKD was 18.32％; the recognition was 1.93％.In addition,the prevalence of albuminuria was respectively 23.79％,28.00％,14.08％; prevalence of reduced eGFR was respectively 4.76％,4.53％,3.26％; prevalence of hematuria was respectively 2.94％,3.20％,2.37％ in 3098 people with hypertension,diabetes or hyperlipaemia.Independent risk factors of albuminuria were female,hypertension,diabetes,hyperlipemia and high BMI.Independent risk factors of reduced eGFR were female,age,hyperuricemia and hypertension.Drink was negatively correlated with reduced eGFR.Independent risk factors of hematuria were female and age.Conclusions The prevalence of CKD is quite high and the recognition rate is low in the Chengdu urban populaton.Risk factors of CKD are age,female,diabetes,hypertension,hyperlipemia,hyperuricemia and high BMI.Control of the development of metabolic disease can reduce the CKD.