CAJ | 학술논문

目的分析维持性血液透析患者钙磷代谢紊乱情况.方法对70例维持性血液透析患者的钙、磷浓度、钙磷浓度乘积及甲状旁腺素(PTH)进行测定,并与K/DOQI指南指标进行比较.结果 70例患者中,≥50岁36例,＜50岁34例,两组血清钙、磷浓度及钙磷乘积、PTH水平比较,差异均无统计学意义(均P＞0.05);透析时间越长,患者血清磷、PTH水平改变越明显,差异有统计学意义(均p＜0.05);70例中有46例(65.7%)血清钙、34例(48.6%)血清磷、40例(57.1%)钙磷乘积、28例(40%)PTH浓度达到K/DOQI指南要求,仅有18例(25.7%)患者所有指标达到K/DOQI要求.结论多数血液透析患者钙磷代谢控制仍然达不到K/DOQI要求的目标.
목적 분석유지성혈액투석환자개린대사문란정황.방법 대70례유지성혈액투석환자적개、린농도、개린농도승적급갑상방선소(PTH)진행측정,병여K/DOQI지남지표진행비교.결과 70례환자중,≥50세36례,＜50세34례,량조혈청개、린농도급개린승적、PTH수평비교,차이균무통계학의의(균P＞0.05);투석시간월장,환자혈청린、PTH수평개변월명현,차이유통계학의의(균p＜0.05);70례중유46례(65.7%)혈청개、34례(48.6%)혈청린、40례(57.1%)개린승적、28례(40%)PTH농도체도K/DOQI지남요구,부유18례(25.7%)환자소유지표체도K/DOQI요구.결론 다수혈액투석환자개린대사공제잉연체불도K/DOQI요구적목표.
Objective To analyze the disorder status of calcium-phosphorus metablism in maintenance hemodialysis patients. Methods Serum calcium, serum phosphorus, calcium-phosphorus product and PTH were detected in 70 patients with maintenance hemodialysis ,and compared with the indicators of K/DOQI guidelines. Results There were 36 cases over 50 years age and 34 cases less than 50 years age in 70 cases, and there were no significant differences in serum calcium, serum phosphorus, calcium-phosphorus product and PTH between two groups (P ＞0.05). The longer the dialysis, the more obvious changes of serum phosphorus and PTH levels, and there were significant differences(P ＜0.05). In 70 cases ,46 cases(65. 7%) serum calcium,34 cases(48.6%) serum phosphorus ,40 cases(57. 1%) calcium and phosphorus product,28 cases(40%) PTH met the requirement of K/DOQI guidelines,only 18 cases (25.7%) of all indicators reached the K/DOQI requirements. Conclusion The calcium-phosphorus metablism in most hemodialytic patients still cannot reach the K/DOQI guidelines.