云南省2000-2007年静脉吸毒者、性病就诊者和孕产妇HIV-1新近感染率及流行趋势变化
운남성2000-2007년정맥흡독자、성병취진자화잉산부HIV-1신근감염솔급류행추세변화
A dynamic analysis on incidence and trend of HIV-1 epidemics among Intravenous Drug Users, attendants at the STD clinics and pregnant women in Yunnan province, China
  • 万方数据
    中华流行病学杂志 중화류행병학잡지
    CHINESE JOURNAL OF EPIDEMIOLOGY
    2008年 12期 1204-1207 ,共4页

    杨莉%马艳玲%罗红兵%贾曼红%杨朝军%王憨杰%陈会超%沈圣%梅静远%田飞%施玉华%闫文云%陆林%蒋岩

    양리%마염령%라홍병%가만홍%양조군%왕감걸%진회초%침골%매정원%전비%시옥화%염문운%륙림%장암

    艾滋病病毒%新近感染率%BED-CEIA检测 艾滋病病毒%新近感染率%BED-CEIA檢測
    애자병병독%신근감염솔%BED-CEIA검측
    Human immunodeficiency virus%Incidence%BED-CEIA assay
    目的 在云南省艾滋病监测哨点用BED-CEIA方法 开展HIV-1新近感染检测,估箅新近感染率和流行趋势.方法 收集2000-2007年云南省静脉吸毒(IDU)监测哨点、性病门诊监测哨点和孕产妇监测哨点样本,采用连续的横断面调查,对经过血清学检测确认为HIV-1阳性样本再进行BED-CEIA检测.结果 研究样本共计144 780份,检出HIV-1阳性样本4932份,完成BED-CEIA检测4678份,判为新近感染样本723份.相邻两年样本合并分析,2000-2007年IDU监测哨点HIV-1平均感染率在18.2%～26.9%之间,新近感染率分别为14.65%、6.21%、4.06%、2.23%;性病门诊监测哨点HIV-1平均感染率在1.6%～3.2%之间,新近感染率分别为1.46%、0.76%、0.52%、0.33%;孕产妇监测哨点HIV-1平均感染率在0.2%～0.5%之间,新近感染率分别为0.16%、0.11%、0.10%、0.09%.结论 三类监测人群中,IDU、性病门诊就诊者和孕产妇新近感染率有所下降.
    목적 재운남성애자병감측초점용BED-CEIA방법 개전HIV-1신근감염검측,고폐신근감염솔화류행추세.방법 수집2000-2007년운남성정맥흡독(IDU)감측초점、성병문진감측초점화잉산부감측초점양본,채용련속적횡단면조사,대경과혈청학검측학인위HIV-1양성양본재진행BED-CEIA검측.결과 연구양본공계144 780빈,검출HIV-1양성양본4932빈,완성BED-CEIA검측4678빈,판위신근감염양본723빈.상린량년양본합병분석,2000-2007년IDU감측초점HIV-1평균감염솔재18.2%～26.9%지간,신근감염솔분별위14.65%、6.21%、4.06%、2.23%;성병문진감측초점HIV-1평균감염솔재1.6%～3.2%지간,신근감염솔분별위1.46%、0.76%、0.52%、0.33%;잉산부감측초점HIV-1평균감염솔재0.2%～0.5%지간,신근감염솔분별위0.16%、0.11%、0.10%、0.09%.결론 삼류감측인군중,IDU、성병문진취진자화잉산부신근감염솔유소하강.
    Objective BED-CEIA assay was used in HIV/AIDS surveillance sentinel sites to identify recent HIV-1 infection, to estimate HIV-1 incidence and to understand the epidemic trends in Yunnan province. Methods Serum specimens were collected from IDUs in sentinel sites, attendants in STD clinics and pregnant women under a cross sectional study from 2000 to 2007. Specimens confirmed as HIV-1 positive were tested with BED-CEIA to find resent HIV-1 infection, then the annual HIV-1 incidence for each group was calculated and the trends of HIV-1 incidence observed. Results 144 780 serum specimens were collected and 4932 of them were confirmed as HIV-1 positive. 4678 positive specimens were tested with BED-CEIA and 723 ont of them were identified as recent infections. Specimens from the two years were combined for testing. The average HIV-1 prevalence among IDUs was 18.2 %-26.9 % from 2000 to 2007 and the annual incidence were 14.65%, 6.21%, 4.06%, 2.23% respectively. The average HIV-1 prevalence among attendants in STD clinics was 1.6 %-3.2 % and the annual incidence rates were 1.46 %, 0.76 %, 0.52 %, 0.33 % respectively. The average HIV-1 prevalence among pregnant women was 0.2%-0.5% and the annual incidence rates were 0.16%, 0.11%, 0.10%, 0.09% respectively. Conclusion HIV-1incidence rates among IDUs, STDs and pregnant women showed a steady decease.
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