中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2011年
8期
676-679
,共4页
连艳凯%李虹伟%吴永全%王永亮%陈晖%赵树梅
連豔凱%李虹偉%吳永全%王永亮%陳暉%趙樹梅
련염개%리홍위%오영전%왕영량%진휘%조수매
冠心病%糖尿病%心室功能障碍,左
冠心病%糖尿病%心室功能障礙,左
관심병%당뇨병%심실공능장애,좌
Coronary disease%Diabetes mellitus%Ventricular dysfunction,left
目的 通过测定左室舒张功能、动脉僵硬度,探讨糖尿病对冠心病患者左室舒张功能和动脉僵硬度的影响,及左室舒张功能与动脉倡硬度之间的相关性.方法 将患者分为对照组、单纯冠心病绀、冠心病合并糖尿病组3组.测得左室舒张末压力(LVEDP)、左室压力衰退时间常数(tan)等左室舒张功能指标及脉搏波速度(c-f PWV)、校正心率后反射波增强指数(AIx@75)等反映患者动脉僵硬度指标.结果 冠心病合并糖尿病组c-fPWV[(8.79±1.59)cm/s]显著高于对照组[(6.83±1.14)cm/s]及单纯冠心病组[(7.43±1.42)cm/s].相关性分析显示AIx@75同tau指数之间存在正性相关性联系.结论 合并糖尿病的冠心病患者同对照组及单纯冠心病组相比动脉僵硬度更差,舒张功能差异未显示出统计学意义;动脉僵硬度同舒张功能不全间可能存在着一定的相关性.
目的 通過測定左室舒張功能、動脈僵硬度,探討糖尿病對冠心病患者左室舒張功能和動脈僵硬度的影響,及左室舒張功能與動脈倡硬度之間的相關性.方法 將患者分為對照組、單純冠心病紺、冠心病閤併糖尿病組3組.測得左室舒張末壓力(LVEDP)、左室壓力衰退時間常數(tan)等左室舒張功能指標及脈搏波速度(c-f PWV)、校正心率後反射波增彊指數(AIx@75)等反映患者動脈僵硬度指標.結果 冠心病閤併糖尿病組c-fPWV[(8.79±1.59)cm/s]顯著高于對照組[(6.83±1.14)cm/s]及單純冠心病組[(7.43±1.42)cm/s].相關性分析顯示AIx@75同tau指數之間存在正性相關性聯繫.結論 閤併糖尿病的冠心病患者同對照組及單純冠心病組相比動脈僵硬度更差,舒張功能差異未顯示齣統計學意義;動脈僵硬度同舒張功能不全間可能存在著一定的相關性.
목적 통과측정좌실서장공능、동맥강경도,탐토당뇨병대관심병환자좌실서장공능화동맥강경도적영향,급좌실서장공능여동맥창경도지간적상관성.방법 장환자분위대조조、단순관심병감、관심병합병당뇨병조3조.측득좌실서장말압력(LVEDP)、좌실압력쇠퇴시간상수(tan)등좌실서장공능지표급맥박파속도(c-f PWV)、교정심솔후반사파증강지수(AIx@75)등반영환자동맥강경도지표.결과 관심병합병당뇨병조c-fPWV[(8.79±1.59)cm/s]현저고우대조조[(6.83±1.14)cm/s]급단순관심병조[(7.43±1.42)cm/s].상관성분석현시AIx@75동tau지수지간존재정성상관성련계.결론 합병당뇨병적관심병환자동대조조급단순관심병조상비동맥강경도경차,서장공능차이미현시출통계학의의;동맥강경도동서장공능불전간가능존재착일정적상관성.
Objectives By measuring left ventricular diastolic function and arterial stiffness,this study aims to probe into the effect of diabetes mellitus(DM) on left ventricular diastolic function and arterial stiffness,and evaluate the correlation between left ventricular diastolic funotion and arterial stiffness.Methods Seventy-six inpatients were enrolled.According to their coronary angiography,OGTF test results and past history of DM,patients were divided into controlled,CHD(coronary heart disease with no DM),and CHD+DM groups.Through invasive hemodynamic monitoring during left ventricular angiography,left ventricular end-diastolic pressure(LVEDP)and tan index were collected.Carotid-femoral pulse wave velocity(c-f PWV),reflected wave augmentation index (AIx@75) and other data reflecting the degree of arterial stiffness were collected bedside with non-invasive means.SPSS 18.0 was used for statistical analysis.Results No significant difference was found between groups for LVEDP,tau index,and AIx@75.In terms of c-f PMV,The CHD+DM group(8.79±1.59)cm/s differed significantly from the CHD group (7.43±1.42)cm/s and the controlled group(6.83±1.14)cm/s.No correlations were found between c-f PMV and LVEDP or tau index.A positive correlation was found between AIx@75 and tau index.Conclusions Compared with the controlled group and CHD patients with no DM,CHD+DM patients show worse arterial stiffness with no difference in ventricular diastolic function.There is a positive correlation between arterial stiffness and diastolic dysfunction.
